{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Richardson M"],"funding":["Health Research Council of New Zealand"],"pagination":["1331-1342"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12273618"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["40(7)"],"pubmed_abstract":["<h4>Background</h4>A previous case series showed that Nocebo Hypothesis Cognitive Behavioral Therapy (NH-CBT) is a promising treatment for Functional Neurological Symptom Disorder (FNSD).<h4>Objectives</h4>To further evaluate the potential efficacy of NH-CBT in participants with FNSD (motor type).<h4>Methods</h4>This phase IIb pilot, randomized, parallel group trial compared the efficacy of NH-CBT (n = 20) with an active control condition (n = 19). Self-report scales of motor and other physical symptoms, psychological variables, and blinded assessor ratings of participants' mobility were administered at baseline, and at 8- and 16-week follow-ups. The primary outcome and endpoint of this trial was the Physical Functioning scale of the Short Form-36 Health Questionnaire (SF-36 PF) at the end"],"journal":["Movement disorders : official journal of the Movement Disorder Society"],"pubmed_title":["Nocebo Hypothesis Cognitive Behavioral Therapy for Functional Neurological Symptom Disorder (Motor Type): A Pilot Randomized Controlled Trial."],"pmcid":["PMC12273618"],"funding_grant_id":["20/045"],"pubmed_authors":["Wong D","Richardson M","Kleinstauber M"],"additional_accession":[]},"is_claimable":false,"name":"Nocebo Hypothesis Cognitive Behavioral Therapy for Functional Neurological Symptom Disorder (Motor Type): A Pilot Randomized Controlled Trial.","description":"<h4>Background</h4>A previous case series showed that Nocebo Hypothesis Cognitive Behavioral Therapy (NH-CBT) is a promising treatment for Functional Neurological Symptom Disorder (FNSD).<h4>Objectives</h4>To further evaluate the potential efficacy of NH-CBT in participants with FNSD (motor type).<h4>Methods</h4>This phase IIb pilot, randomized, parallel group trial compared the efficacy of NH-CBT (n = 20) with an active control condition (n = 19). Self-report scales of motor and other physical symptoms, psychological variables, and blinded assessor ratings of participants' mobility were administered at baseline, and at 8- and 16-week follow-ups. The primary outcome and endpoint of this trial was the Physical Functioning scale of the Short Form-36 Health Questionnaire (SF-36 PF) at the end","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2026-03-18T13:54:39.577Z","creation":"2025-08-21T09:52:58.091Z"},"accession":"S-EPMC12273618","cross_references":{"pubmed":["40353675"],"doi":["10.1002/mds.30195"]}}