{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(7)"],"submitter":["Khodarahmi M"],"pubmed_abstract":["Chronic low-grade inflammation is a probable mediator between the quantity of carbohydrate intake and health outcomes. The aim of this systematic review and meta-analysis of randomized clinical trials (RCTs) was to summarize the effects of low carbohydrate diets (LCDs) as compared to control diets on c-reactive protein (CRP) levels in adults. A comprehensive search was conducted in several databases up to February 2024. In total, 60 eligible trials with 5511 adults were included in the meta-analysis. LCDs resulted in an average reduction of 0.18 mg/L in CRP levels compared to control groups (MD = 0.18; 95% CI: 0.032 to 0.03; <i>p</i> = 0.016); however, sensitivity analysis revealed that this significance was dependent on a single study (Abbaspour Rad et al.), with exclusion of which the ef"],"journal":["Food science & nutrition"],"pagination":["e70566"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12274166"],"repository":["biostudies-literature"],"pubmed_title":["Effect of Low-Carbohydrate Diets on C-Reactive Protein Level in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials."],"pmcid":["PMC12274166"],"pubmed_authors":["Khodarahmi M","Seyedhosseini H","Askari G"],"additional_accession":[]},"is_claimable":false,"name":"Effect of Low-Carbohydrate Diets on C-Reactive Protein Level in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","description":"Chronic low-grade inflammation is a probable mediator between the quantity of carbohydrate intake and health outcomes. The aim of this systematic review and meta-analysis of randomized clinical trials (RCTs) was to summarize the effects of low carbohydrate diets (LCDs) as compared to control diets on c-reactive protein (CRP) levels in adults. A comprehensive search was conducted in several databases up to February 2024. In total, 60 eligible trials with 5511 adults were included in the meta-analysis. LCDs resulted in an average reduction of 0.18 mg/L in CRP levels compared to control groups (MD = 0.18; 95% CI: 0.032 to 0.03; <i>p</i> = 0.016); however, sensitivity analysis revealed that this significance was dependent on a single study (Abbaspour Rad et al.), with exclusion of which the ef","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2026-03-18T14:16:29.848Z","creation":"2025-08-23T03:08:54.522Z"},"accession":"S-EPMC12274166","cross_references":{"pubmed":["40688603"],"doi":["10.1002/fsn3.70566"]}}