{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29(1)"],"submitter":["Habeeb TAAM"],"funding":["Zagazig University"],"pubmed_abstract":["<h4>Purpose</h4>Giant sliding hiatal hernias (HH) are prevalent in the elderly population (EP) and often present with multiple comorbidities and a high surgical risk. Frailty has been increasingly recognized as a predictor of surgical outcomes in the EP. This study assessed the rate of recurrent sliding HH following mesh cruroplasty and laparoscopic Nissen fundoplication (LNF), and evaluated frailty as a potential risk factor of recurrence.<h4>Methods</h4>This retrospective multicenter study included 266 patients aged ≥ 60 years who underwent mesh cruroplasty and LNF for giant sliding HH (> 5 cm) with severe reflux esophagitis (Demeester score > 100) between March 2016 and March 2022, stratified into non-recurrence (n = 241) and recurrence (n = 25) HH.<h4>Results</h4>The mean age was 66.92"],"journal":["Hernia : the journal of hernias and abdominal wall surgery"],"pagination":["235"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12274264"],"repository":["biostudies-literature"],"pubmed_title":["Frailty predicts recurrence after laparoscopic Nissen fundoplication with mesh cruroplasty for giant sliding hiatal hernia with severe reflux esophagitis in elderly patients: a multicenter retrospective study."],"pmcid":["PMC12274264"],"pubmed_authors":["Nimeri A","Arafa AS","Kryvoruchko IA","Elias AA","Ali RMM","Teama SRA","Habeeb TAAM","Naguib SM","Chiaretti M","Youssef MZ","Zaid MAA","Heggy IA","Shamy IAME","Lledo JB","Elshafey MH","Seleem A","Gadallah MA","Elnemr M","Elbelkasi H","Awad ETK","Hamdy A","Hussain A","Ahmed SMA","Kermansaravi M","Alsayed MH","Abozaid M","El Teliti AM","Mostafa A","Abdelwanis AH","Khyrallh A","Aiolfi A","Mostafa MMS","Labib MF","Elshahidy TM","Abdelaziz AM","Khairy MM","Wasefy T","Nawar AMH","Alsaad MIA"],"additional_accession":[]},"is_claimable":false,"name":"Frailty predicts recurrence after laparoscopic Nissen fundoplication with mesh cruroplasty for giant sliding hiatal hernia with severe reflux esophagitis in elderly patients: a multicenter retrospective study.","description":"<h4>Purpose</h4>Giant sliding hiatal hernias (HH) are prevalent in the elderly population (EP) and often present with multiple comorbidities and a high surgical risk. Frailty has been increasingly recognized as a predictor of surgical outcomes in the EP. This study assessed the rate of recurrent sliding HH following mesh cruroplasty and laparoscopic Nissen fundoplication (LNF), and evaluated frailty as a potential risk factor of recurrence.<h4>Methods</h4>This retrospective multicenter study included 266 patients aged ≥ 60 years who underwent mesh cruroplasty and LNF for giant sliding HH (> 5 cm) with severe reflux esophagitis (Demeester score > 100) between March 2016 and March 2022, stratified into non-recurrence (n = 241) and recurrence (n = 25) HH.<h4>Results</h4>The mean age was 66.92","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2026-07-15T09:00:33.562Z","creation":"2025-08-23T03:09:11.017Z"},"accession":"S-EPMC12274264","cross_references":{"pubmed":["40679643"],"doi":["10.1007/s10029-025-03416-6"]}}