biostudies-literatureUnknown29(1)Habeeb TAAMZagazig University<h4>Purpose</h4>Giant sliding hiatal hernias (HH) are prevalent in the elderly population (EP) and often present with multiple comorbidities and a high surgical risk. Frailty has been increasingly recognized as a predictor of surgical outcomes in the EP. This study assessed the rate of recurrent sliding HH following mesh cruroplasty and laparoscopic Nissen fundoplication (LNF), and evaluated frailty as a potential risk factor of recurrence.<h4>Methods</h4>This retrospective multicenter study included 266 patients aged ≥ 60 years who underwent mesh cruroplasty and LNF for giant sliding HH (> 5 cm) with severe reflux esophagitis (Demeester score > 100) between March 2016 and March 2022, stratified into non-recurrence (n = 241) and recurrence (n = 25) HH.<h4>Results</h4>The mean age was 66.92Hernia : the journal of hernias and abdominal wall surgery235https://www.ebi.ac.uk/biostudies/studies/S-EPMC12274264biostudies-literatureFrailty predicts recurrence after laparoscopic Nissen fundoplication with mesh cruroplasty for giant sliding hiatal hernia with severe reflux esophagitis in elderly patients: a multicenter retrospective study.PMC12274264Nimeri AArafa ASKryvoruchko IAElias AAAli RMMTeama SRAHabeeb TAAMNaguib SMChiaretti MYoussef MZZaid MAAHeggy IAShamy IAMELledo JBElshafey MHSeleem AGadallah MAElnemr MElbelkasi HAwad ETKHamdy AHussain AAhmed SMAKermansaravi MAlsayed MHAbozaid MEl Teliti AMMostafa AAbdelwanis AHKhyrallh AAiolfi AMostafa MMSLabib MFElshahidy TMAbdelaziz AMKhairy MMWasefy TNawar AMHAlsaad MIAfalseFrailty predicts recurrence after laparoscopic Nissen fundoplication with mesh cruroplasty for giant sliding hiatal hernia with severe reflux esophagitis in elderly patients: a multicenter retrospective study.<h4>Purpose</h4>Giant sliding hiatal hernias (HH) are prevalent in the elderly population (EP) and often present with multiple comorbidities and a high surgical risk. Frailty has been increasingly recognized as a predictor of surgical outcomes in the EP. This study assessed the rate of recurrent sliding HH following mesh cruroplasty and laparoscopic Nissen fundoplication (LNF), and evaluated frailty as a potential risk factor of recurrence.<h4>Methods</h4>This retrospective multicenter study included 266 patients aged ≥ 60 years who underwent mesh cruroplasty and LNF for giant sliding HH (> 5 cm) with severe reflux esophagitis (Demeester score > 100) between March 2016 and March 2022, stratified into non-recurrence (n = 241) and recurrence (n = 25) HH.<h4>Results</h4>The mean age was 66.922025-01-01T00:00:00Z2025 Jul2026-07-15T09:00:33.562Z2025-08-23T03:09:11.017ZS-EPMC122742644067964310.1007/s10029-025-03416-6