biostudies-literatureBenedict KIntramural CDC HHSmyaf049https://www.ebi.ac.uk/biostudies/studies/S-EPMC12281149biostudies-literatureUnknown63(6)We conservatively estimated the annual US fungal disease-related economic burden as $19.4 billion, including direct medical costs ($13.4 billion) of hospitalizations (n = 133 555) and outpatient visits (n = 13.4 million), $1.7 billion from absenteeism, and $4.3 billion from deaths (n = 7288). These findings underscore the need for fungal disease surveillance, treatment, and prevention efforts.Medical mycologyEconomic burden of fungal diseases in the United States.PMC12281149CC999999Gold JAWBenedict KChiller TLyman MfalseEconomic burden of fungal diseases in the United States.We conservatively estimated the annual US fungal disease-related economic burden as $19.4 billion, including direct medical costs ($13.4 billion) of hospitalizations (n = 133 555) and outpatient visits (n = 13.4 million), $1.7 billion from absenteeism, and $4.3 billion from deaths (n = 7288). These findings underscore the need for fungal disease surveillance, treatment, and prevention efforts.2025-01-01T00:00:00Z2025 Jun2026-03-27T16:53:46.729Z2025-08-28T03:08:56.057ZS-EPMC122811494045558610.1093/mmy/myaf049