{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Farizano JV"],"funding":["Consejo Nacional de Investigaciones Científicas y Técnicas","Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación"],"pagination":["1624743"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12286952"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16"],"pubmed_abstract":["Indwelling devices, such as double-J stents, are commonly used in urological surgery and are often associated with a high risk of urinary tract infections (UTIs) due to biofilm-related complications. In this study, we characterized 27 clinical bacterial isolates from double-J catheters, including <i>Staphylococcus</i> spp., <i>Enterococcus faecalis, Klebsiella pneumoniae, Escherichia coli</i>, and <i>Bacillus</i> spp., to investigate their pathogenic potential. Our findings revealed that strong biofilm producers (<i>E. coli, S. aureus</i>, and <i>B. subtilis</i>) exhibited robust extracellular matrix synthesis. Notably, multidrug resistance was observed in <i>E. coli, K. pneumoniae</i>, and <i>E. faecalis</i>. Mixed-culture experiments demonstrated that <i>Bacillus</i> spp. enhanced the bi"],"journal":["Frontiers in microbiology"],"pubmed_title":["Virulence traits and bacterial interactions within the complex microbial population in urinary double-J catheters."],"pmcid":["PMC12286952"],"funding_grant_id":["PIP11220200103262CO","PICT-2021-CAT-I-00159","PICT 02977","PICT 2021-GRF-TI-00306"],"pubmed_authors":["Castagnaro E","Arroyo-Egea JT","Farizano JV","Vallejos AC","Saavedra L","Grillo-Puertas M","Aparicio JD","Rapisarda VA","Villegas JM","Hebert EM"],"additional_accession":[]},"is_claimable":false,"name":"Virulence traits and bacterial interactions within the complex microbial population in urinary double-J catheters.","description":"Indwelling devices, such as double-J stents, are commonly used in urological surgery and are often associated with a high risk of urinary tract infections (UTIs) due to biofilm-related complications. In this study, we characterized 27 clinical bacterial isolates from double-J catheters, including <i>Staphylococcus</i> spp., <i>Enterococcus faecalis, Klebsiella pneumoniae, Escherichia coli</i>, and <i>Bacillus</i> spp., to investigate their pathogenic potential. Our findings revealed that strong biofilm producers (<i>E. coli, S. aureus</i>, and <i>B. subtilis</i>) exhibited robust extracellular matrix synthesis. Notably, multidrug resistance was observed in <i>E. coli, K. pneumoniae</i>, and <i>E. faecalis</i>. Mixed-culture experiments demonstrated that <i>Bacillus</i> spp. enhanced the bi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-29T05:02:36.964Z","creation":"2025-08-17T03:06:04.582Z"},"accession":"S-EPMC12286952","cross_references":{"pubmed":["40708917"],"doi":["10.3389/fmicb.2025.1624743"]}}