{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["487(1)"],"submitter":["Mansour Y"],"funding":["Alma Mater Studiorum - Università di Bologna"],"pubmed_abstract":["With the reclassification of non-invasive follicular variant of papillary thyroid carcinoma as \"tumors\" (NIFTP), the challenge of diagnosing carcinoma lies in recognizing invasion: blood vessel invasion (BVI) or capsular invasion (CI). We aimed to assess reproducibility in diagnosing BVI and CI in follicular-patterned tumors using a web-platform, under conditions as close as possible to routine surgical pathology practice. Six-hundred-fourteen pathologists reviewed 69 thyroid lesions diagnostically challenging for BVI or CI, made available in three rounds: before, immediately after, and three months after a training lecture given by an expert pathologist. Each lesion was associated with a quiz (five queries: certain CI, doubtful CI, certain BVI, doubtful BVI, or no invasion). Intraobserver"],"journal":["Virchows Archiv : an international journal of pathology"],"pagination":["105-116"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12289735"],"repository":["biostudies-literature"],"pubmed_title":["Can we improve the diagnosis of invasion in encapsulated follicular-patterned thyroid tumors? Data from a massive international e-learning initiative."],"pmcid":["PMC12289735"],"pubmed_authors":["Cavillon A","Belleannee G","Al Bouzidi A","Sobrinho-Simoes M","De Leo A","Mansour Y","Mrad K","Tallini G","Ramiandrasoa AL","Vibert N","Vielh P","Chaltiel L","Kamate B"],"additional_accession":[]},"is_claimable":false,"name":"Can we improve the diagnosis of invasion in encapsulated follicular-patterned thyroid tumors? Data from a massive international e-learning initiative.","description":"With the reclassification of non-invasive follicular variant of papillary thyroid carcinoma as \"tumors\" (NIFTP), the challenge of diagnosing carcinoma lies in recognizing invasion: blood vessel invasion (BVI) or capsular invasion (CI). We aimed to assess reproducibility in diagnosing BVI and CI in follicular-patterned tumors using a web-platform, under conditions as close as possible to routine surgical pathology practice. Six-hundred-fourteen pathologists reviewed 69 thyroid lesions diagnostically challenging for BVI or CI, made available in three rounds: before, immediately after, and three months after a training lecture given by an expert pathologist. Each lesion was associated with a quiz (five queries: certain CI, doubtful CI, certain BVI, doubtful BVI, or no invasion). Intraobserver","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2026-03-17T13:41:10.97Z","creation":"2025-08-16T03:05:20.574Z"},"accession":"S-EPMC12289735","cross_references":{"pubmed":["39992439"],"doi":["10.1007/s00428-025-04045-1"]}}