{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["73(8)"],"submitter":["Kayawake H"],"pubmed_abstract":["<h4>Objectives</h4>Generally, HLA matching between donors and recipients is not performed in lung transplantation (LTx). Therefore, whether HLA mismatch between donors and recipients (D/R mismatch) influences postoperative outcomes after LTx remains uncertain. In this study, we investigated the influence of D/R mismatch on postoperative outcomes after cadaveric LTx (CLT).<h4>Methods</h4>A total of 140 CLT procedures were performed between 2012 and 2020. After excluding 5 recipients with preformed DSA and 1 recipient undergoing re-LTx, 134 recipients were enrolled in this retrospective study. The postoperative outcomes were compared between recipients with higher and lower D/R mismatches.<h4>Results</h4>The median D/R mismatch (A/B/DR loci) was 4.0 (range, 1-6). When dividing these 134 reci"],"journal":["General thoracic and cardiovascular surgery"],"pagination":["609-615"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12289801"],"repository":["biostudies-literature"],"pubmed_title":["Influence of HLA mismatch between donors and recipients on postoperative outcomes in cadaveric lung transplantation."],"pmcid":["PMC12289801"],"pubmed_authors":["Ryo T","Date H","Sakanoue I","Matsumoto A","Matsubara T","Tanaka S","Yutaka Y","Nakajima D","Nishino Y","Kayawake H"],"additional_accession":[]},"is_claimable":false,"name":"Influence of HLA mismatch between donors and recipients on postoperative outcomes in cadaveric lung transplantation.","description":"<h4>Objectives</h4>Generally, HLA matching between donors and recipients is not performed in lung transplantation (LTx). Therefore, whether HLA mismatch between donors and recipients (D/R mismatch) influences postoperative outcomes after LTx remains uncertain. In this study, we investigated the influence of D/R mismatch on postoperative outcomes after cadaveric LTx (CLT).<h4>Methods</h4>A total of 140 CLT procedures were performed between 2012 and 2020. After excluding 5 recipients with preformed DSA and 1 recipient undergoing re-LTx, 134 recipients were enrolled in this retrospective study. The postoperative outcomes were compared between recipients with higher and lower D/R mismatches.<h4>Results</h4>The median D/R mismatch (A/B/DR loci) was 4.0 (range, 1-6). When dividing these 134 reci","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-03-27T17:07:19.144Z","creation":"2025-08-28T03:09:21.585Z"},"accession":"S-EPMC12289801","cross_references":{"pubmed":["39652304"],"doi":["10.1007/s11748-024-02109-8"]}}