{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nie T"],"funding":["kunpeng cui","jiahui wang","luwang"],"pagination":["1474"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12297972"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(7)"],"pubmed_abstract":["The strain of <i>Oceanobacillus picturae</i> DY09, as a typical halophilic microorganism, possesses distinctive salt adaptation mechanisms that hold significant application value in the fields of agriculture, industry, and biomedicine. To deeply analyze the salt-tolerance molecular mechanism of this strain, this research disclosed its salt-tolerance strategies under diverse salt concentrations through transcriptomics. In a low-salt environment, the DY09 strain adopted a \"metabolic simplification\" strategy, significantly reducing the metabolic load by promoting lysine degradation and inhibiting the biosynthesis of branched-chain amino acids and glycine betaine (GB) but upregulating the expression of the GB transporter gene <i>betH</i> and preferentially utilizing exogenous GB to maintain ba"],"journal":["Microorganisms"],"pubmed_title":["A Halophilic Bacterium for Bioremediation of Saline-Alkali Land: The Triadic and Synergetic Response Mechanism of &lt;i&gt;Oceanobacillus picturae&lt;/i&gt; DY09 to Salt Stress."],"pmcid":["PMC12297972"],"funding_grant_id":["ZR2024QD159","ZR2023QB272","ZR2022QC177"],"pubmed_authors":["Liu Y","Nie T","Fu S","Cui K","Wang J","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"A Halophilic Bacterium for Bioremediation of Saline-Alkali Land: The Triadic and Synergetic Response Mechanism of &lt;i&gt;Oceanobacillus picturae&lt;/i&gt; DY09 to Salt Stress.","description":"The strain of <i>Oceanobacillus picturae</i> DY09, as a typical halophilic microorganism, possesses distinctive salt adaptation mechanisms that hold significant application value in the fields of agriculture, industry, and biomedicine. To deeply analyze the salt-tolerance molecular mechanism of this strain, this research disclosed its salt-tolerance strategies under diverse salt concentrations through transcriptomics. In a low-salt environment, the DY09 strain adopted a \"metabolic simplification\" strategy, significantly reducing the metabolic load by promoting lysine degradation and inhibiting the biosynthesis of branched-chain amino acids and glycine betaine (GB) but upregulating the expression of the GB transporter gene <i>betH</i> and preferentially utilizing exogenous GB to maintain ba","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jun","modification":"2025-08-14T03:05:49.351Z","creation":"2025-08-14T03:05:49.351Z"},"accession":"S-EPMC12297972","cross_references":{"pubmed":["40731984"],"doi":["10.3390/microorganisms13071474"]}}