{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["74"],"submitter":["Farag MA"],"funding":["Alexander von Humboldt-Stiftung"],"pubmed_abstract":["<h4>Introduction</h4>Climate change poses various threats to marine life, particularly in shallow tropical waters.<h4>Objective</h4>The impact of increased temperature and ultraviolet (UV) exposure on two photosymbiotic cnidarians, a common bubble-tip anemone and an upside-down jellyfish, was investigated.<h4>Methods</h4>To illustrate the response of aquatic organisms, the metabolomes of unstressed Entacmaea quadricolor and Cassiopea andromeda were compared for detailed metabolite profiling. UHPLC-MS coupled with chemometrics and GNPS molecular networking was employed for sample classification and identification of markers unique to stress responses in each organism.<h4>Results</h4>Several compounds with bioactive functions, including peptides and terpenoids, were reported for the first ti"],"journal":["Journal of advanced research"],"pagination":["255-268"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12302363"],"repository":["biostudies-literature"],"pubmed_title":["Metabolic responses of sea anemone and jellyfish to temperature and UV bleaching: Insights into stress adaptation using LCMS-based metabolomics, molecular networking and chemometrics."],"pmcid":["PMC12302363"],"pubmed_authors":["Afifi SM","Stuhr M","Kunzmann A","Wessjohann LA","Farag MA","Saied DB","Kuhnhold H","Westphal H"],"additional_accession":[]},"is_claimable":false,"name":"Metabolic responses of sea anemone and jellyfish to temperature and UV bleaching: Insights into stress adaptation using LCMS-based metabolomics, molecular networking and chemometrics.","description":"<h4>Introduction</h4>Climate change poses various threats to marine life, particularly in shallow tropical waters.<h4>Objective</h4>The impact of increased temperature and ultraviolet (UV) exposure on two photosymbiotic cnidarians, a common bubble-tip anemone and an upside-down jellyfish, was investigated.<h4>Methods</h4>To illustrate the response of aquatic organisms, the metabolomes of unstressed Entacmaea quadricolor and Cassiopea andromeda were compared for detailed metabolite profiling. UHPLC-MS coupled with chemometrics and GNPS molecular networking was employed for sample classification and identification of markers unique to stress responses in each organism.<h4>Results</h4>Several compounds with bioactive functions, including peptides and terpenoids, were reported for the first ti","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-03-27T17:01:13.49Z","creation":"2025-08-28T03:09:13.19Z"},"accession":"S-EPMC12302363","cross_references":{"pubmed":["39414229"],"doi":["10.1016/j.jare.2024.10.007"]}}