biostudies-literatureUnknown13Harvey PR<h4>Background and study aims</h4>National data suggest that biliary drainage for malignant obstruction is associated with high complication rates and early mortality. This study examined factors associated with poor outcomes.<h4>Patients and methods</h4>RICOCHET was a national, prospective audit of patients with pancreatic cancer or malignant biliary obstruction between April and August 2018. This analysis reviewed outcomes including complications within 7 days and 30-day mortality following biliary drainage and associated factors.<h4>Results</h4>Biliary drainage was attempted in 773 patients, of which, 78.7% were successful at first attempt; but if unsuccessful, only 37% of subsequent attempts succeeded. Complications occurred following 11% of endoscopic retrograde cholangiopancreatograpEndoscopy international opena25586754https://www.ebi.ac.uk/biostudies/studies/S-EPMC12303028biostudies-literatureOutcomes and complications of biliary drainage for malignant biliary obstruction: National prospective study.PMC12303028Wilkin RRTrudgill NLayton GRMohamed SAHarvey PRRoberts KPowell-Brett SMcKay SCfalseOutcomes and complications of biliary drainage for malignant biliary obstruction: National prospective study.<h4>Background and study aims</h4>National data suggest that biliary drainage for malignant obstruction is associated with high complication rates and early mortality. This study examined factors associated with poor outcomes.<h4>Patients and methods</h4>RICOCHET was a national, prospective audit of patients with pancreatic cancer or malignant biliary obstruction between April and August 2018. This analysis reviewed outcomes including complications within 7 days and 30-day mortality following biliary drainage and associated factors.<h4>Results</h4>Biliary drainage was attempted in 773 patients, of which, 78.7% were successful at first attempt; but if unsuccessful, only 37% of subsequent attempts succeeded. Complications occurred following 11% of endoscopic retrograde cholangiopancreatograp2025-01-01T00:00:00Z20252026-03-16T14:54:33.035Z2025-08-15T03:07:12.697ZS-EPMC123030284072653010.1055/a-2558-6754