{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Yakdan S"],"funding":["NIMH NIH HHS","NIAMS NIH HHS"],"pubmed_abstract":["<h4>Study design</h4>Prospective cohort study.<h4>Objective</h4>This study aims to define Substantial Clinical Benefit (SCB) thresholds for PROMIS physical function (PF) and pain interference (PI) in lumbar or thoracolumbar spine surgery population.<h4>Summary of background data</h4>Patient-reported outcome measures (PROMs) are widely used in spine surgery to assess treatment efficacy. SCB is a relatively new concept that represents a substantial improvement perceived by the patient.<h4>Methods</h4>This is a prospective study that included adults aged 21-85 years, undergoing lumbar/ thoracolumbar surgery for degenerative spine disease, and reporting at least 3/10 back or leg pain on a numeric rating scale. PROMs including Oswestry Disability Index, PROMIS PF, and PROMIS PI were collected p"],"journal":["Spine"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12307724"],"repository":["biostudies-literature"],"pubmed_title":["Defining Substantial Clinical Benefits of PROMIS Pain Interference and Physical Function in Patients Undergoing Lumbar and Thoracolumbar Spine Surgery."],"pmcid":["PMC12307724"],"funding_grant_id":["K23 AR082986","F31 MH124291"],"pubmed_authors":["Zhang JK","Goodin BR","Plog BA","Ray WZ","Kelly MP","Piccirillo JF","Yakdan S","Buchowski JM","Rodebaugh TL","Greenberg JK","Benedict B","Botterbush K","Javeed S","Frumkin MR"],"additional_accession":[]},"is_claimable":false,"name":"Defining Substantial Clinical Benefits of PROMIS Pain Interference and Physical Function in Patients Undergoing Lumbar and Thoracolumbar Spine Surgery.","description":"<h4>Study design</h4>Prospective cohort study.<h4>Objective</h4>This study aims to define Substantial Clinical Benefit (SCB) thresholds for PROMIS physical function (PF) and pain interference (PI) in lumbar or thoracolumbar spine surgery population.<h4>Summary of background data</h4>Patient-reported outcome measures (PROMs) are widely used in spine surgery to assess treatment efficacy. SCB is a relatively new concept that represents a substantial improvement perceived by the patient.<h4>Methods</h4>This is a prospective study that included adults aged 21-85 years, undergoing lumbar/ thoracolumbar surgery for degenerative spine disease, and reporting at least 3/10 back or leg pain on a numeric rating scale. PROMs including Oswestry Disability Index, PROMIS PF, and PROMIS PI were collected p","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-06-14T03:13:11.807Z","creation":"2026-06-14T03:08:42.274Z"},"accession":"S-EPMC12307724","cross_references":{"pubmed":["39882633"],"doi":["10.1097/BRS.0000000000005276","10.1097/brs.0000000000005276"]}}