biostudies-literatureUnknownYakdan SNIMH NIH HHSNIAMS NIH HHS<h4>Study design</h4>Prospective cohort study.<h4>Objective</h4>This study aims to define Substantial Clinical Benefit (SCB) thresholds for PROMIS physical function (PF) and pain interference (PI) in lumbar or thoracolumbar spine surgery population.<h4>Summary of background data</h4>Patient-reported outcome measures (PROMs) are widely used in spine surgery to assess treatment efficacy. SCB is a relatively new concept that represents a substantial improvement perceived by the patient.<h4>Methods</h4>This is a prospective study that included adults aged 21-85 years, undergoing lumbar/ thoracolumbar surgery for degenerative spine disease, and reporting at least 3/10 back or leg pain on a numeric rating scale. PROMs including Oswestry Disability Index, PROMIS PF, and PROMIS PI were collected pSpinehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC12307724biostudies-literatureDefining Substantial Clinical Benefits of PROMIS Pain Interference and Physical Function in Patients Undergoing Lumbar and Thoracolumbar Spine Surgery.PMC12307724K23 AR082986F31 MH124291Zhang JKGoodin BRPlog BARay WZKelly MPPiccirillo JFYakdan SBuchowski JMRodebaugh TLGreenberg JKBenedict BBotterbush KJaveed SFrumkin MRfalseDefining Substantial Clinical Benefits of PROMIS Pain Interference and Physical Function in Patients Undergoing Lumbar and Thoracolumbar Spine Surgery.<h4>Study design</h4>Prospective cohort study.<h4>Objective</h4>This study aims to define Substantial Clinical Benefit (SCB) thresholds for PROMIS physical function (PF) and pain interference (PI) in lumbar or thoracolumbar spine surgery population.<h4>Summary of background data</h4>Patient-reported outcome measures (PROMs) are widely used in spine surgery to assess treatment efficacy. SCB is a relatively new concept that represents a substantial improvement perceived by the patient.<h4>Methods</h4>This is a prospective study that included adults aged 21-85 years, undergoing lumbar/ thoracolumbar surgery for degenerative spine disease, and reporting at least 3/10 back or leg pain on a numeric rating scale. PROMs including Oswestry Disability Index, PROMIS PF, and PROMIS PI were collected p2025-01-01T00:00:00Z2025 Jan2026-06-14T03:13:11.807Z2026-06-14T03:08:42.274ZS-EPMC123077243988263310.1097/BRS.000000000000527610.1097/brs.0000000000005276