biostudies-literatureUnknown19Baccaredda Boy O<h4>Introduction</h4>The study aims to evaluate symptomatic differences through psychometric tools comparing patients in the early stages of psychotic development with those exhibiting a more established symptomatology. Our hypothesis was that the early phase in adolescent patients is accompanied by quantitatively and qualitatively distinct symptomatology compared to adults.<h4>Methods</h4>We assessed 116 participants-consisting of 14 to 65 years old patients with psychotic or mood symptoms-using psychometric tools and a clinical interview. The tools explored psychotic, depressive and anxiety dimensions, to provide a multifaceted assessment of the recruited individuals and help at categorizing them into diagnostic subclasses.<h4>Results</h4>We compared patients with psychotic symptoms (earFrontiers in behavioral neuroscience1614730https://www.ebi.ac.uk/biostudies/studies/S-EPMC12321885biostudies-literatureMulti-domain destructuring in the early phases of psychosis: a multicentric phenomenological and psychometric case-control study.PMC12321885Pitt GBozza BMerola GPPapini LPatti AFlaccomio DPisano TBaccaredda Boy OTavano SGori SRicca VNoschese IDe Cesaris FPecoraro VMauceri FDi Matteo EFaldi MRicci CBallerini ACiabattini SBrugnolo DCohen DPeroni GfalseMulti-domain destructuring in the early phases of psychosis: a multicentric phenomenological and psychometric case-control study.<h4>Introduction</h4>The study aims to evaluate symptomatic differences through psychometric tools comparing patients in the early stages of psychotic development with those exhibiting a more established symptomatology. Our hypothesis was that the early phase in adolescent patients is accompanied by quantitatively and qualitatively distinct symptomatology compared to adults.<h4>Methods</h4>We assessed 116 participants-consisting of 14 to 65 years old patients with psychotic or mood symptoms-using psychometric tools and a clinical interview. The tools explored psychotic, depressive and anxiety dimensions, to provide a multifaceted assessment of the recruited individuals and help at categorizing them into diagnostic subclasses.<h4>Results</h4>We compared patients with psychotic symptoms (ear2025-01-01T00:00:00Z20252026-03-31T11:46:16.504Z2025-09-01T03:06:07.915ZS-EPMC123218854076696210.3389/fnbeh.2025.1614730