biostudies-literatureWhittaker HBritish Heart Foundation466-477https://www.ebi.ac.uk/biostudies/studies/S-EPMC12322415biostudies-literatureUnknown80(7)<h4>Background</h4>We describe the epidemiology of asthma, chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) from 2004 to 2023 in England, Wales, Scotland and Northern Ireland (NI) using a harmonised approach.<h4>Methods</h4>Data from the National Health Service England (NHSE), Clinical Practice Research Datalink Aurum in England, Secure Anonymised Information Linkage Databank in Wales, DataLoch in South-East Scotland and the Honest Broker Service in NI were used. A harmonised approach to COPD, asthma and ILD case definitions, study designs and study populations across the four nations was performed. Age-sex-standardised incidence rates and point prevalence were calculated between 2004 and 2023 depending on data availability. Logistic and negative binomial reThoraxIncidence and prevalence of asthma, chronic obstructive pulmonary disease and interstitial lung disease between 2004 and 2023: harmonised analyses of longitudinal cohorts across England, Wales, South-East Scotland and Northern Ireland.PMC12322415SP/19/3/34678Greaves FIvanovic AForsyth RNg FSEvans HTTNafilyan VSiyu CBerthon WAbdel Douiri AOChinoy HPerera GCVD-COVID-UK/COVID-IMPACT ConsortiumJenkins DMu YGasparrini AWalker VRichardson HHFletcher RGomes MMurdock LHealey RDocherty AMcDonagh TZhu ZFleetwood KBolton TMandal SWong EChoo LPherwani AMacleod JAkyea RCrowe SWhite BQuinn TLorgelly PHarshfield EHigginson IMamas MCripps RPape TBirney EHidajat MKolamunnage-Dona RDong TRao SHippisley-Cox JSaunders KMachado PBromage DHemingway HPriedon RGilbert RHalcox JBusby JSuseeladevi AKWilde HMartelli JLCurry GLax SBath PElwenspoek MEspuny-Pujol FIslam NHosking ALai AJohnson SPadmanabhan STayal PScully SAbbasizanjani HToms RBen Bray CWKhalid SBone ADale CSelby DGajendragadkar PDennis JZaccagnino FHarris DLawler DCezard GPetersen SNikiphorou ESanchez NOliver DOliver CWhiteley WHama TMarsland AAhmed NWhitfield ESudell MAngelantonio EDSterne JWalter IFriebel RLyons JSampri AHinchliffe RKeller ENjie BLyons RHardelid PCook SKraljevic ZRaffetti EMcLennan NMelville CRazieh CKent SNorris RThomas MSperrin MOnyeachu PKeene SKontopantelis ECannata AKhunti KLogothetis SBMason SSpiliopoulou AHolloway SDas-Munshi JTran DWatkinson RMizani MReynolds RSingh AShabnam SWood ATzoulaki ICromwell DLambarth AKnight RHamada YHarron KChilala CBuch MConstantine AGlickman MRathod KLang NSchmidt FFrain SCurcin VYates TWatson HTatuene JKBen Goldacre BLSudlow CKaptoge SBlackbourn LCaputo MNicholson GGu QDenholm RPierotti LTungamirai TBabu-Narayan SMatthewman JDoorn CVCheema KHenning EHeyl JHocaoglu MGillies CBown MCarson APavey HHardy FUppal AKeavney BFarrell JStrafford HPennells LStone PHarrison CHansell ASofat RWalker EBarrett JNorth LHarrison HDelmestri AKallis CSchwartz RSmith CChilman NMohamed MLawrence TKramer Fiala Machado AMarshall IShah ALyon MSheppard JBiglarbeigi PKhan NKhan SWilliams MKurdi AWarwick AWright LWilliams GDashtban AMcGranahan MOnida SBrind DSteeg STaylor KPatel RBenton LFalter FJohn AColhoun HWang HIMalgapo ECabreira VHall NChin RSydes MSilva TNartey YSosenko FPinho-Gomes ACDickson AMacleod MJWilliams SGurdasani DWilliams RCruz AStevenson KSheikh AWithnell EJones DTakhar RMarchant AZhao SKelly EDregan ACroft SAldridge RLaunders NHorne EFalck FWebb MSherlock LBrodin PGreen MTorabi FPetitjean CHasheminasab SAWebb APickrell OBidulka PThompson AMellor JAjaib SADowns JDalakoti MHatam SChukwusa EPorter TFirth JLyratzopoulos YInouye MOlvera-Barrios AKatsoulis MFraser LSau AChudasama YRahimi KTilston GNitsch DLewis JFitzgerald RFitzgerald TLilaonitkul WEvans HLi QZhong XLi KLi LAllara EWilkinson TMason ALi YPasea LSchnier CBriffa NQuint JKBanos MDPBacon SMorris CDhillon BCleland JArab MAFeltz-Cornelis CVBen Gibbison DMRonaldson AAyyar-Gupta VEllins EAChaudhry SJackson CDanesh JJackson AGrundmann AJiang XIve JMorris ESchofield DMcKeever SWelshman ZRashid MAllery FQuint JZeissler MLWakefield DBell SParbery-Clark CBennie MLooker KShelton JDavies AProvidencia RZhang HUnwin JAngelini GShi WConrad NKillick RAkbari AMartin GChalmers FTufail ASoriano CSWalsh EHughes DZuckerman BZaccardi FFriday JPearce FChan JMadley-Dowd PYiu ZNewman JKerr SKasan JEllershaw SBojanic LDavies NBeveridge JDavies JCanoy DPearce NPrieto-Alhambra DChang JADavies GKinnear DNadarajah RHenderson AMueller TSlapkova MMordi IWhittaker HSleeman KOsborn DKim LToit CDArafin RDeo SSattar NHeaney LGMapeta RPowell DKavanagh KDhiman PSalim SLawson CZhou MGoldacre RKarim ZRitson MSquire ILlinares MBPirmohamed MKim SAustin JAllen MPell JQian LWareing NGerstung MWu JFord JTata LTorralbo AZuccolo LHollings ABraithwaite TMorales DMorrice LDenaxas SLangan SWang HPearn KChico THuang QCarroll CBarber MWu HTownson JLowe DMichael BWang SWang TIp SWang XGrieco LTaleshmekaeil ZBBerry CMcKinney EAntonarou ADenniston AHo FThygesen JStevenson ASinha SO'Connell DMoncusi MPKhawaja ASze SO'Connell MKee FTochel CTomlinson CMamouei MBanerjee APagel CYavlinsky ARutter MRogers CProudfoot APalmer TRossdale JBecares LNolan JKing DHandy ABehr EPastika LPalmer ABrown KfalseIncidence and prevalence of asthma, chronic obstructive pulmonary disease and interstitial lung disease between 2004 and 2023: harmonised analyses of longitudinal cohorts across England, Wales, South-East Scotland and Northern Ireland.<h4>Background</h4>We describe the epidemiology of asthma, chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) from 2004 to 2023 in England, Wales, Scotland and Northern Ireland (NI) using a harmonised approach.<h4>Methods</h4>Data from the National Health Service England (NHSE), Clinical Practice Research Datalink Aurum in England, Secure Anonymised Information Linkage Databank in Wales, DataLoch in South-East Scotland and the Honest Broker Service in NI were used. A harmonised approach to COPD, asthma and ILD case definitions, study designs and study populations across the four nations was performed. Age-sex-standardised incidence rates and point prevalence were calculated between 2004 and 2023 depending on data availability. Logistic and negative binomial re2025-01-01T00:00:00Z2025 Jun2026-03-27T17:13:19.609Z2025-08-30T03:09:18.538ZS-EPMC123224154019958810.1136/thorax-2024-222699