{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gottschalk S"],"funding":["European Union’s Horizon 2020 research and innovation programme"],"pagination":["683-690"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12322465"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(7)"],"pubmed_abstract":["<h4>Background</h4>Recent studies, including the TENSION trial, support the use of endovascular thrombectomy (EVT) in acute ischemic stroke with large infarct (Alberta Stroke Program Early Computed Tomography Score (ASPECTS) 3-5).<h4>Objective</h4>To evaluate the cost-effectiveness of EVT compared with best medical care (BMC) alone in this population from a German healthcare payer perspective.<h4>Methods</h4>A short-term decision tree and a long-term Markov model (lifetime horizon) were used to compare healthcare costs and quality-adjusted life years (QALYs) between EVT and BMC. The effectiveness of EVT was reflected by the 90-day modified Rankin Scale (mRS) outcome from the TENSION trial. QALYs were based on published mRS-specific health utilities (EQ-5D-3L indices). Long-term healthcare "],"journal":["Journal of neurointerventional surgery"],"pubmed_title":["Cost-effectiveness of endovascular thrombectomy for acute ischemic stroke with established large infarct in Germany: a decision tree and Markov model."],"pmcid":["PMC12322465"],"funding_grant_id":["754640"],"pubmed_authors":["Bendszus M","Bonekamp S","Thomalla G","Zelenak K","Krajina A","Simonsen CZ","Hill MD","Gottschalk S","Aamodt AH","Konig HH","Fuentes B","Gizewski ER","Subtil F","Pierot L","Denis A","Dams J"],"additional_accession":[]},"is_claimable":false,"name":"Cost-effectiveness of endovascular thrombectomy for acute ischemic stroke with established large infarct in Germany: a decision tree and Markov model.","description":"<h4>Background</h4>Recent studies, including the TENSION trial, support the use of endovascular thrombectomy (EVT) in acute ischemic stroke with large infarct (Alberta Stroke Program Early Computed Tomography Score (ASPECTS) 3-5).<h4>Objective</h4>To evaluate the cost-effectiveness of EVT compared with best medical care (BMC) alone in this population from a German healthcare payer perspective.<h4>Methods</h4>A short-term decision tree and a long-term Markov model (lifetime horizon) were used to compare healthcare costs and quality-adjusted life years (QALYs) between EVT and BMC. The effectiveness of EVT was reflected by the 90-day modified Rankin Scale (mRS) outcome from the TENSION trial. QALYs were based on published mRS-specific health utilities (EQ-5D-3L indices). Long-term healthcare ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jun","modification":"2026-07-15T12:51:11.335Z","creation":"2025-09-01T03:05:56.518Z"},"accession":"S-EPMC12322465","cross_references":{"pubmed":["38906688"],"doi":["10.1136/jnis-2024-021837"]}}