biostudies-literatureUnknown111(15)Sun L<h4>Background</h4>The Prognostic Nutritional Index (PNI), calculated from serum albumin levels and lymphocyte counts, is a simple and objective measure of nutritional status. While PNI has been shown to be a significant prognostic tool in gastrointestinal surgery and heart failure, its role in patients undergoing coronary artery bypass grafting (CABG) remains unclear. This study aims to evaluate whether PNI can serve as a meaningful risk factor for patients undergoing CABG.<h4>Methods</h4>This observational retrospective analysis involved a substantial sample of 2889 patients who underwent isolated CABG at one of four medical centres. The primary outcomes included short- and long-term mortality. Perioperative serum albumin levels and total lymphocyte counts used to calculate PNIs were colHeart (British Cardiac Society)722-732https://www.ebi.ac.uk/biostudies/studies/S-EPMC12322477biostudies-literatureImpact of prognostic nutritional index on mortality among patients receiving coronary artery bypass grafting surgery: a retrospective cohort study.PMC12322477Xu KDong WPan YHan LCui XHu BSun YZhao XSun LLi WLiu ZLi ZZhang YWang ZfalseImpact of prognostic nutritional index on mortality among patients receiving coronary artery bypass grafting surgery: a retrospective cohort study.<h4>Background</h4>The Prognostic Nutritional Index (PNI), calculated from serum albumin levels and lymphocyte counts, is a simple and objective measure of nutritional status. While PNI has been shown to be a significant prognostic tool in gastrointestinal surgery and heart failure, its role in patients undergoing coronary artery bypass grafting (CABG) remains unclear. This study aims to evaluate whether PNI can serve as a meaningful risk factor for patients undergoing CABG.<h4>Methods</h4>This observational retrospective analysis involved a substantial sample of 2889 patients who underwent isolated CABG at one of four medical centres. The primary outcomes included short- and long-term mortality. Perioperative serum albumin levels and total lymphocyte counts used to calculate PNIs were col2025-01-01T00:00:00Z2025 Jul2026-03-31T11:35:52.897Z2025-08-31T03:08:34.131ZS-EPMC123224773993390810.1136/heartjnl-2024-324471