{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ouyang H"],"funding":["Hong Kong Polytechnic University","Research Grants Council"],"pagination":["108"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12325440"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["Post-stroke fracture risk necessitates investigation of bone properties and contributing factors. The decline in paretic tibia failure load post-stroke was attributed to decreased trabecular bone density and thickness at 2-year follow-up. Less decline in bone strength was associated with better leg blood flow, walking speed, strength, and activity at baseline.Purpose
To delineate long-term changes in distal tibia bone properties after stroke and identify their associated factors.Methods
High-resolution peripheral quantitative computed tomography (HR-pQCT) scans of the bilateral distal tibia were performed in 46 chronic stroke participants (age, 60.4 ± 7.8 years; post-stroke onset, 6.3 ± 4.2 years) and 45 controls (age, 57.7 ± 6.3 years) at baseline and 2 years later. We mea"],"journal":["Archives of osteoporosis"],"pubmed_title":["Longitudinal bone loss in the paretic leg and its contributing factors in individuals with chronic stroke: a 2-year prospective cohort study."],"pmcid":["PMC12325440"],"funding_grant_id":["PhD studentship","General Research Fund: 151031/18M"],"pubmed_authors":["Hung VWY","Ying MTC","Qin L","Ouyang H","Miller T","Leung TWH","Pang MYC"],"additional_accession":[]},"is_claimable":false,"name":"Longitudinal bone loss in the paretic leg and its contributing factors in individuals with chronic stroke: a 2-year prospective cohort study.","description":"Post-stroke fracture risk necessitates investigation of bone properties and contributing factors. The decline in paretic tibia failure load post-stroke was attributed to decreased trabecular bone density and thickness at 2-year follow-up. Less decline in bone strength was associated with better leg blood flow, walking speed, strength, and activity at baseline.Purpose
To delineate long-term changes in distal tibia bone properties after stroke and identify their associated factors.Methods
High-resolution peripheral quantitative computed tomography (HR-pQCT) scans of the bilateral distal tibia were performed in 46 chronic stroke participants (age, 60.4 ± 7.8 years; post-stroke onset, 6.3 ± 4.2 years) and 45 controls (age, 57.7 ± 6.3 years) at baseline and 2 years later. We mea","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-03-31T11:59:06.771Z","creation":"2025-09-01T03:08:27.5Z"},"accession":"S-EPMC12325440","cross_references":{"pubmed":["40764456"],"doi":["10.1007/s11657-025-01541-4"]}}