{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Du Toit G"],"funding":["NIAID NIH HHS","Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["1435-43"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12333932"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["374(15)"],"pubmed_abstract":["<h4>Background</h4>In a randomized trial, the early introduction of peanuts in infants at high risk for allergy was shown to prevent peanut allergy. In this follow-up study, we investigated whether the rate of peanut allergy remained low after 12 months of peanut avoidance among participants who had consumed peanuts during the primary trial (peanut-consumption group), as compared with those who had avoided peanuts (peanut-avoidance group).<h4>Methods</h4>At the end of the primary trial, we instructed all the participants to avoid peanuts for 12 months. The primary outcome was the percentage of participants with peanut allergy at the end of the 12-month period, when the participants were 72 months of age.<h4>Results</h4>We enrolled 556 of 628 eligible participants (88.5%) from the primary t"],"journal":["The New England journal of medicine"],"pubmed_title":["Effect of Avoidance on Peanut Allergy after Early Peanut Consumption."],"pmcid":["PMC12333932"],"funding_grant_id":["HHSN272200800029C","UM1AI109565","UM1 AI109565","G0902018","G1000758","UM2AI117870","N01-AI-15416","MR/M008517/1"],"pubmed_authors":["Harris KM","Adam M","Richards K","Wu C","O'Dwyer-Leeson U","Witham N","Deutsch G","Crossley M","Lack G","Turcanu V","Stephens A","Watson F","Francisco Ndo C","Abraham M","Plaut M","Immune Tolerance Network LEAP-On Study Team","Chan S","Fox A","Santos AF","Nixon A","Cleaver R","Heath J","Fisher H","Sudra A","Patkunam D","Sayre PH","Brough HA","Whitehouse D","Barton M","Wester R","Miller T","Panza JL","Plough A","Lawson K","Feeney M","Sever ML","Mason T","Asare A","Sheridan A","Basting M","Hersee K","Chani E","Parr A","Harland G","Duncan C","Cockerell K","Becares N","Bahnson HT","Coverdale L","Offord V","Wilson A","Radulovic S","McCachren S","Clarke C","Lorenzo MG","Pietraszewicz E","Evind J","Stedman C","Lim N","Du Toit G","Roberts G"],"additional_accession":[]},"is_claimable":false,"name":"Effect of Avoidance on Peanut Allergy after Early Peanut Consumption.","description":"<h4>Background</h4>In a randomized trial, the early introduction of peanuts in infants at high risk for allergy was shown to prevent peanut allergy. In this follow-up study, we investigated whether the rate of peanut allergy remained low after 12 months of peanut avoidance among participants who had consumed peanuts during the primary trial (peanut-consumption group), as compared with those who had avoided peanuts (peanut-avoidance group).<h4>Methods</h4>At the end of the primary trial, we instructed all the participants to avoid peanuts for 12 months. The primary outcome was the percentage of participants with peanut allergy at the end of the 12-month period, when the participants were 72 months of age.<h4>Results</h4>We enrolled 556 of 628 eligible participants (88.5%) from the primary t","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Apr","modification":"2026-05-01T08:35:43.404Z","creation":"2026-04-07T16:47:06.731Z"},"accession":"S-EPMC12333932","cross_references":{"pubmed":["26942922"],"doi":["10.1056/nejmoa1514209","10.1056/NEJMoa1514209"]}}