biostudies-literatureUnknown104(7)Lopez-Fernandez E<h4>Objective</h4>The EORTC QLQ-CML24 questionnaire was developed and validated to enhance research in the health-related quality of life (HRQoL) of patients with chronic myeloid leukemia (CML) as a way to more thoroughly capture the burden of disease and therapy and facilitate treatment decisions in this population. We aimed to examine the structure and psychometric properties of the Spanish version.<h4>Methods</h4>Data were collected from 186 CML patients in 9 centers of Andalusia (Spain). The validation process integrated the analysis of feasibility, internal consistency, construct validity and convergent validity. The core EORTC QLQ-C30, Short Form-36 (SF-36), Hospital Anxiety and Depression Scale (HADS) and the Connor-Davison Resilience Scale (CD-RISC-10) were used to assess convergenAnnals of hematology3693-3702https://www.ebi.ac.uk/biostudies/studies/S-EPMC12334532biostudies-literatureValidation of the Spanish version of the EORTC QLQ-CML24 questionnaire for assessment of health-related quality of life in patients with chronic myeloid leukemia.PMC12334532de Linares-Fernandez SGonzalez-Molina WAnguita-Arance MDel Carmen Fernandez-Valle MPerez-Marfil MNVera-Goni JAFerrer-Chaves CPuerta-Puerta JMLopez-Fernandez ERamirez-Sanchez MJRuiz-Nuno MCAvellaneda-Molina CfalseValidation of the Spanish version of the EORTC QLQ-CML24 questionnaire for assessment of health-related quality of life in patients with chronic myeloid leukemia.<h4>Objective</h4>The EORTC QLQ-CML24 questionnaire was developed and validated to enhance research in the health-related quality of life (HRQoL) of patients with chronic myeloid leukemia (CML) as a way to more thoroughly capture the burden of disease and therapy and facilitate treatment decisions in this population. We aimed to examine the structure and psychometric properties of the Spanish version.<h4>Methods</h4>Data were collected from 186 CML patients in 9 centers of Andalusia (Spain). The validation process integrated the analysis of feasibility, internal consistency, construct validity and convergent validity. The core EORTC QLQ-C30, Short Form-36 (SF-36), Hospital Anxiety and Depression Scale (HADS) and the Connor-Davison Resilience Scale (CD-RISC-10) were used to assess convergen2025-01-01T00:00:00Z2025 Jul2026-06-03T07:08:34.795Z2026-05-29T03:05:54.857ZS-EPMC123345324069407710.1007/s00277-025-06516-6