{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["66(11)"],"submitter":["Wu Y"],"pubmed_abstract":["Purpose
To investigate the arrangement and orientation of the collagen fibers in the inner and outer scleral layers at the edges of posterior staphylomas using polarization-sensitive optical coherence tomography (PS-OCT).Methods
This observational case series study enrolled 105 patients with high myopia (refractive error <-6.0 diopters or axial length ≥26.5 mm) who underwent PS-OCT examinations between August 2023 and May 2024 at the Institute of Science Tokyo. Posterior staphyloma was diagnosed in 88 eyes of 60 patients using ultra-widefield OCT, followed by PS-OCT image processing. Thirty-six eyes from 27 patients with clearly identifiable staphyloma edges were included for final analysis. PS-OCT images were analyzed to assess the scleral fiber orientation and birefringen"],"journal":["Investigative ophthalmology & visual science"],"pagination":["6"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12338364"],"repository":["biostudies-literature"],"pubmed_title":["Polarization-Sensitive Optical Coherence Tomography Imaging of Posterior Staphyloma Edges in Eyes With High Myopia."],"pmcid":["PMC12338364"],"pubmed_authors":["Xiong J","Okamoto M","Yamanari M","Chen C","Sugisawa K","Kamoi K","Takahashi T","Lu H","Ohno-Matsui K","Wang Y","Wang Z","Wu Y","Takahashi H"],"additional_accession":[]},"is_claimable":false,"name":"Polarization-Sensitive Optical Coherence Tomography Imaging of Posterior Staphyloma Edges in Eyes With High Myopia.","description":"Purpose
To investigate the arrangement and orientation of the collagen fibers in the inner and outer scleral layers at the edges of posterior staphylomas using polarization-sensitive optical coherence tomography (PS-OCT).Methods
This observational case series study enrolled 105 patients with high myopia (refractive error <-6.0 diopters or axial length ≥26.5 mm) who underwent PS-OCT examinations between August 2023 and May 2024 at the Institute of Science Tokyo. Posterior staphyloma was diagnosed in 88 eyes of 60 patients using ultra-widefield OCT, followed by PS-OCT image processing. Thirty-six eyes from 27 patients with clearly identifiable staphyloma edges were included for final analysis. PS-OCT images were analyzed to assess the scleral fiber orientation and birefringen","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-04T15:24:47.893Z","creation":"2026-04-07T20:38:44.725Z"},"accession":"S-EPMC12338364","cross_references":{"pubmed":["40762541"],"doi":["10.1167/iovs.66.11.6"]}}