{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(8)"],"submitter":["Li J"],"pubmed_abstract":["<h4>Purpose</h4>The purpose of this study was to identify novel features on spectral-domain optical coherence tomography angiography (SD-OCTA) that improve detection of polypoidal lesions in polypoidal choroidal vasculopathy (PCV).<h4>Methods</h4>In this prospective study, 22 eyes from 20 patients with indocyanine green angiography (ICGA) confirmed PCV underwent same-day imaging with both SD-OCTA and swept-source OCTA (SS-OCTA). Images were independently reviewed, and blinded to ICGA and each other. Morphological features of polypoidal lesions were compared to establish combined diagnostic criteria to improve SD-OCTA detection, including hyper- or hypo-flow signals on angiographic en face images, circular hypo-reflective signals on structural en face images, and corresponding flow signals "],"journal":["Translational vision science & technology"],"pagination":["12"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12338367"],"repository":["biostudies-literature"],"pubmed_title":["Combining Hypo-Reflective Structural En Face Imaging Improves Polypoidal Lesion Detection on Spectral-Domain OCT Angiography."],"pmcid":["PMC12338367"],"pubmed_authors":["Zhou M","Shen M","Bo Q","Xu N","Li J","Jia H","Wang F","Wan X","Sun X"],"additional_accession":[]},"is_claimable":false,"name":"Combining Hypo-Reflective Structural En Face Imaging Improves Polypoidal Lesion Detection on Spectral-Domain OCT Angiography.","description":"<h4>Purpose</h4>The purpose of this study was to identify novel features on spectral-domain optical coherence tomography angiography (SD-OCTA) that improve detection of polypoidal lesions in polypoidal choroidal vasculopathy (PCV).<h4>Methods</h4>In this prospective study, 22 eyes from 20 patients with indocyanine green angiography (ICGA) confirmed PCV underwent same-day imaging with both SD-OCTA and swept-source OCTA (SS-OCTA). Images were independently reviewed, and blinded to ICGA and each other. Morphological features of polypoidal lesions were compared to establish combined diagnostic criteria to improve SD-OCTA detection, including hyper- or hypo-flow signals on angiographic en face images, circular hypo-reflective signals on structural en face images, and corresponding flow signals ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-04-18T11:16:12.729Z","creation":"2026-04-07T14:34:33.14Z"},"accession":"S-EPMC12338367","cross_references":{"pubmed":["40762535"],"doi":["10.1167/tvst.14.8.12"]}}