{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bosserman RE"],"funding":["bioMérieux SA"],"pagination":["e0021125"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12345239"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["63(8)"],"pubmed_abstract":["Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is widely used for rapid identification of bacteria and yeast in clinical labs. The VITEK MS PRIME (\"PRIME\") is the latest MALDI-TOF MS system from bioMérieux. This study evaluated PRIME's performance and workflow timing against the MALDI Biotyper CA System by Bruker (\"Biotyper\"). We compared a collection of 154 bacteria and yeast clinical isolates from various specimen types using three methods: Biotyper target with a toothpick, PRIME target with the PICKME nib, and PRIME target with a loop. Positive blood culture isolates were also analyzed using these methods, with high-experience (HEU, <i>n</i> = 300) and low-experience users (LEU, <i>n</i> = 50) after short (6-8 h) and routine (18-24 h) incubat"],"journal":["Journal of clinical microbiology"],"pubmed_title":["Performance and workflow comparison of the VITEK MS PRIME and Bruker Biotyper MALDI-TOF MS systems."],"pmcid":["PMC12345239"],"funding_grant_id":["n/a"],"pubmed_authors":["Alvarado K","Yarbrough ML","Bosserman RE","Roemmich B","Tarlton NJ"],"additional_accession":[]},"is_claimable":false,"name":"Performance and workflow comparison of the VITEK MS PRIME and Bruker Biotyper MALDI-TOF MS systems.","description":"Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is widely used for rapid identification of bacteria and yeast in clinical labs. The VITEK MS PRIME (\"PRIME\") is the latest MALDI-TOF MS system from bioMérieux. This study evaluated PRIME's performance and workflow timing against the MALDI Biotyper CA System by Bruker (\"Biotyper\"). We compared a collection of 154 bacteria and yeast clinical isolates from various specimen types using three methods: Biotyper target with a toothpick, PRIME target with the PICKME nib, and PRIME target with a loop. Positive blood culture isolates were also analyzed using these methods, with high-experience (HEU, <i>n</i> = 300) and low-experience users (LEU, <i>n</i> = 50) after short (6-8 h) and routine (18-24 h) incubat","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-29T14:27:13.277Z","creation":"2026-04-08T05:04:47.016Z"},"accession":"S-EPMC12345239","cross_references":{"pubmed":["40539832"],"doi":["10.1128/jcm.00211-25"]}}