{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tsilochristou O"],"funding":["Asthma UK","Food Standards Agency","Food Allergy Research &amp; Education","NIAID NIH HHS","National Institutes of Health","Clemens von Pirquet Foundation","NIH","NIAID","National Institute of Allergy and Infectious Diseases","National Peanut Board","Biomedical Research Centre","UK Department of Health","Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["494-503"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12351383"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["144(2)"],"pubmed_abstract":["<h4>Background</h4>Staphylococcus aureus has been implicated in the pathophysiology of eczema, allergic rhinitis, asthma, and food allergy. S aureus is a marker of more severe eczema, which is a risk factor for food sensitization/allergy. Therefore it might be that the association between S aureus and food allergy in eczematous patients is related to eczema severity.<h4>Objective</h4>We sought to investigate the association of S aureus colonization with specific IgE (sIgE) production to common food allergens and allergies in early childhood independent of eczema severity. We additionally determined the association of S aureus colonization with eczema severity and persistence.<h4>Methods</h4>In Learning Early About Peanut Allergy (LEAP) study participants eczema severity was assessed, and s"],"journal":["The Journal of allergy and clinical immunology"],"pubmed_title":["Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity."],"pmcid":["PMC12351383"],"funding_grant_id":["UM2 AI117870","HHSN272200800029C","UM1AI109565","N01 AI015416","UM1 AI109565","UM2AI117870","NO1-AI-15416"],"pubmed_authors":["Adam M","Richards K","Wu C","Tsilochristou O","du Toit G","O'Dwyer-Leeson U","Witham N","Deutsch G","Crossley M","Lack G","Stephens A","Watson F","Abraham M","Plaut M","Chan S","Fox A","Nixon A","Cleaver R","Heath J","Fisher H","Francisco NDC","Sudra A","Hu J","Patkunam D","Sayre PH","Lussier S","Whitehouse D","Wester R","Miller T","Panza JL","Plough A","Lawson K","Sever ML","Mason T","Asare A","Sheridan A","Basting M","Hersee K","Chani E","Parr A","Immune Tolerance Network Learning Early About Peanut Allergy Study Team","Harland G","Duncan C","Cockerell K","Becares N","Bahnson HT","Coverdale L","Offord V","Wilson A","Radulovic S","Clarke C","Lorenzo MG","Pietraszewicz E","Evind J","Stedman C","Lim N","Roberts G"],"additional_accession":[]},"is_claimable":false,"name":"Association of Staphylococcus aureus colonization with food allergy occurs independently of eczema severity.","description":"<h4>Background</h4>Staphylococcus aureus has been implicated in the pathophysiology of eczema, allergic rhinitis, asthma, and food allergy. S aureus is a marker of more severe eczema, which is a risk factor for food sensitization/allergy. Therefore it might be that the association between S aureus and food allergy in eczematous patients is related to eczema severity.<h4>Objective</h4>We sought to investigate the association of S aureus colonization with specific IgE (sIgE) production to common food allergens and allergies in early childhood independent of eczema severity. We additionally determined the association of S aureus colonization with eczema severity and persistence.<h4>Methods</h4>In Learning Early About Peanut Allergy (LEAP) study participants eczema severity was assessed, and s","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Aug","modification":"2026-04-13T07:07:14.991Z","creation":"2026-04-07T13:24:40.975Z"},"accession":"S-EPMC12351383","cross_references":{"pubmed":["31160034"],"doi":["10.1016/j.jaci.2019.04.025"]}}