{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Uea-Anuwong T"],"funding":["City University of Hong Kong"],"pagination":["101158"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12354790"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21"],"pubmed_abstract":["Leptospirosis is a zoonotic bacterial disease that has a global impact on human and animal health. Rats are known as natural reservoirs of pathogenic <i>Leptospira</i> species. In the Hong Kong Special Administrative Region (SAR), the infection status of peridomestic rat species is not known. In this study, 250 rats belonging to four species (<i>Rattus norvegicus</i>, <i>R. tanezumi</i>, <i>R. andamanensis</i>, and <i>Niviventer huang</i>) were sampled from different ecological habitats across Hong Kong SAR in 2019, 2020, and 2022. The DNA extracted from the kidney tissues of the rats were screened using a polymerase chain reaction (PCR) for the pathogen-specific leptospiral gene <i>lipL32</i>. The positive samples were then confirmed by PCR targeting the <i>lfb-1</i> gene and were further"],"journal":["One health (Amsterdam, Netherlands)"],"pubmed_title":["Detection of pathogenic &lt;i&gt;Leptospira&lt;/i&gt; spp. in peridomestic &lt;i&gt;Rattus norvegicus&lt;/i&gt; in Hong Kong."],"pmcid":["PMC12354790"],"funding_grant_id":["9610449"],"pubmed_authors":["Uea-Anuwong T","Thibeaux R","Li F","Magouras I","Wen C","Qing H"],"additional_accession":[]},"is_claimable":false,"name":"Detection of pathogenic &lt;i&gt;Leptospira&lt;/i&gt; spp. in peridomestic &lt;i&gt;Rattus norvegicus&lt;/i&gt; in Hong Kong.","description":"Leptospirosis is a zoonotic bacterial disease that has a global impact on human and animal health. Rats are known as natural reservoirs of pathogenic <i>Leptospira</i> species. In the Hong Kong Special Administrative Region (SAR), the infection status of peridomestic rat species is not known. In this study, 250 rats belonging to four species (<i>Rattus norvegicus</i>, <i>R. tanezumi</i>, <i>R. andamanensis</i>, and <i>Niviventer huang</i>) were sampled from different ecological habitats across Hong Kong SAR in 2019, 2020, and 2022. The DNA extracted from the kidney tissues of the rats were screened using a polymerase chain reaction (PCR) for the pathogen-specific leptospiral gene <i>lipL32</i>. The positive samples were then confirmed by PCR targeting the <i>lfb-1</i> gene and were further","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-04-08T15:48:54.745Z","creation":"2026-04-08T05:36:05.561Z"},"accession":"S-EPMC12354790","cross_references":{"pubmed":["40822317"],"doi":["10.1016/j.onehlt.2025.101158"]}}