biostudies-literatureUnknown27(3)Sevillano-Garayoa LThis study was supported by funding from the Association of Friends of the University of Navarra (Asociación de Amigos de la Universidad de Navarra) and the Santander BankThe rising prevalence of advanced illness poses growing challenges for family caregivers, requiring healthcare professionals to address an increasing array of caregiver needs. This systematic review explores the impact of at-home interventions for caregivers supporting individuals with advanced illness, examining intervention characteristics and methodological quality. Quantitative studies published over the past 5 years (2019-2024) were sourced from PubMed, PsycINFO, CINAHL, Scopus, and Cochrane Library. Intervention data, including modality, components, timing, providers, recipients, and caregiver outcomes, were systematically reviewed. Methodological quality was assessed using Cochrane RoB 2 and ROBINS-I. From 16 studies, key caregiver needs such as depression, anxiety, distress, qualitNursing & health sciencese70196https://www.ebi.ac.uk/biostudies/studies/S-EPMC12358210biostudies-literatureInterventions for Caregivers Caring for a Family Member With Advanced Illness at Home: A Systematic Review.PMC12358210Martin-Martin JOlano-Lizarraga MSevillano-Garayoa LfalseInterventions for Caregivers Caring for a Family Member With Advanced Illness at Home: A Systematic Review.The rising prevalence of advanced illness poses growing challenges for family caregivers, requiring healthcare professionals to address an increasing array of caregiver needs. This systematic review explores the impact of at-home interventions for caregivers supporting individuals with advanced illness, examining intervention characteristics and methodological quality. Quantitative studies published over the past 5 years (2019-2024) were sourced from PubMed, PsycINFO, CINAHL, Scopus, and Cochrane Library. Intervention data, including modality, components, timing, providers, recipients, and caregiver outcomes, were systematically reviewed. Methodological quality was assessed using Cochrane RoB 2 and ROBINS-I. From 16 studies, key caregiver needs such as depression, anxiety, distress, qualit2025-01-01T00:00:00Z2025 Sep2026-05-01T22:55:16.628Z2026-04-07T17:21:16.956ZS-EPMC123582104081966110.1111/nhs.70196