biostudies-literatureUnknown15(8)Shen Y<h4>Purpose</h4>The Kun-Qi birth cohort (KQBC) was established to investigate the incidence, aetiology and risk factors of chronic kidney disease (CKD) in early childhood (0-6 years). Additionally, the study analysed developmental phenotypic trajectories and their associated paediatric diseases.<h4>Participants</h4>Infants registered or residing in Kunshan and Qidong, Jiangsu Province, who participated in the Chinese Child Healthcare Programme (0-6 years) were enrolled. The baseline population was stratified into enhanced and basic cohorts. General characteristics, periconceptional and perinatal information and health check-up data were collected from each participant. Dual screening (urinary ultrasound and urine dipstick tests) was conducted during scheduled check-ups. Structured CKD quesBMJ opene102702https://www.ebi.ac.uk/biostudies/studies/S-EPMC12359510biostudies-literatureKun-Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile.PMC12359510Wu JShen JShen QHuang JWu NWu BShi WZhang LShen HZhang QShi XQiu WGuo LSu RGu CChen ZChen XGu KShen YShen XSun JSheng WLi HJin QYang KChen LXie LXie NSun WXu HXue ZYuan HSun YKQBC groupLi YXu SLu PFeng PDing FLiu HLiu JMi JHan XMa YLiu TLiu YTang MZhai YXu BSong RZhou CGong LWei JMo WZhou HYu XTian JYan JTai MGu YZhuang WJi JZhou XZhu MHuang YZhu JShi BPan CZhang YHuang XCao YZhang XQian QfalseKun-Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile.<h4>Purpose</h4>The Kun-Qi birth cohort (KQBC) was established to investigate the incidence, aetiology and risk factors of chronic kidney disease (CKD) in early childhood (0-6 years). Additionally, the study analysed developmental phenotypic trajectories and their associated paediatric diseases.<h4>Participants</h4>Infants registered or residing in Kunshan and Qidong, Jiangsu Province, who participated in the Chinese Child Healthcare Programme (0-6 years) were enrolled. The baseline population was stratified into enhanced and basic cohorts. General characteristics, periconceptional and perinatal information and health check-up data were collected from each participant. Dual screening (urinary ultrasound and urine dipstick tests) was conducted during scheduled check-ups. Structured CKD ques2025-01-01T00:00:00Z2025 Aug2026-05-29T17:08:36.589Z2026-04-08T05:28:02.829ZS-EPMC123595104081987510.1136/bmjopen-2025-102702