{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5"],"submitter":["Fuoco D"],"pubmed_abstract":["In recent years, there has been a significant increase in literature on emerging nanotechnologies, including nanoparticles, nanorobots, and exosomes, for various therapeutic applications. Additionally, politically driven research initiatives aimed at accelerating COVID-19 vaccine development have further amplified interest in nanoparticles as drug delivery systems. This article provides a personal perspective on the scientific claims surrounding nanoparticles by: (i) analyzing the historical evolution of their terminology, (ii) reviewing the most cited publications in the field, and (iii) offering a professional assessment to guide the next-generation of medicinal chemists. A key aspect of this discussion is the stealth effect, which refers to the ability of nanoparticles to evade recognit"],"journal":["Frontiers in drug delivery"],"pagination":["1564120"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12360436"],"repository":["biostudies-literature"],"pubmed_title":["The stealth effect from a medicinal chemist perspective: definition and updates."],"pmcid":["PMC12360436"],"pubmed_authors":["Fuoco D"],"additional_accession":[]},"is_claimable":false,"name":"The stealth effect from a medicinal chemist perspective: definition and updates.","description":"In recent years, there has been a significant increase in literature on emerging nanotechnologies, including nanoparticles, nanorobots, and exosomes, for various therapeutic applications. Additionally, politically driven research initiatives aimed at accelerating COVID-19 vaccine development have further amplified interest in nanoparticles as drug delivery systems. This article provides a personal perspective on the scientific claims surrounding nanoparticles by: (i) analyzing the historical evolution of their terminology, (ii) reviewing the most cited publications in the field, and (iii) offering a professional assessment to guide the next-generation of medicinal chemists. A key aspect of this discussion is the stealth effect, which refers to the ability of nanoparticles to evade recognit","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-05T12:35:17.121Z","creation":"2026-04-07T21:42:12.456Z"},"accession":"S-EPMC12360436","cross_references":{"pubmed":["40837707"],"doi":["10.3389/fddev.2025.1564120"]}}