{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Carson JL"],"funding":["NHLBI NIH HHS"],"pagination":["EVIDoa2400223"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12367329"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["4(2)"],"pubmed_abstract":["<h4>Background</h4>Clinical guidelines have concluded that there are insufficient data to provide recommendations for the hemoglobin threshold for the use of red cell transfusion in patients with acute myocardial infarction (MI) and anemia. After the recent publication of the Myocardial Infarction and Transfusion (MINT) trial, we performed an individual patient-level data meta-analysis to evaluate the effect of restrictive versus liberal blood transfusion strategies.<h4>Methods</h4>We conducted searches in major databases. Eligible trials randomly assigned patients with MI and anemia to either a restrictive (i.e., transfusion threshold of 7-8 g/dl) or liberal (i.e., transfusion threshold of 10 g/dl) red cell transfusion strategy. We used individual patient data from each trial. The primary"],"journal":["NEJM evidence"],"pubmed_title":["Restrictive versus Liberal Transfusion in Myocardial Infarction - A Patient-Level Meta-Analysis."],"pmcid":["PMC12367329"],"funding_grant_id":["R01 HL171977"],"pubmed_authors":["Steg PG","Cooper H","Portela GT","Mallick R","Menegus MA","Brooks MM","Carson JL","Noveck H","Simon T","Triulzi DJ","Bertolet M","Goldsweig AM","Kim S","Fergusson DA","Goodman SG","Alexander JH","Rao SV","Ducrocq G","Stanworth SJ","Lopes RD","Abbott JD","Hebert PC","DeFilippis AP"],"additional_accession":[]},"is_claimable":false,"name":"Restrictive versus Liberal Transfusion in Myocardial Infarction - A Patient-Level Meta-Analysis.","description":"<h4>Background</h4>Clinical guidelines have concluded that there are insufficient data to provide recommendations for the hemoglobin threshold for the use of red cell transfusion in patients with acute myocardial infarction (MI) and anemia. After the recent publication of the Myocardial Infarction and Transfusion (MINT) trial, we performed an individual patient-level data meta-analysis to evaluate the effect of restrictive versus liberal blood transfusion strategies.<h4>Methods</h4>We conducted searches in major databases. Eligible trials randomly assigned patients with MI and anemia to either a restrictive (i.e., transfusion threshold of 7-8 g/dl) or liberal (i.e., transfusion threshold of 10 g/dl) red cell transfusion strategy. We used individual patient data from each trial. The primary","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2026-05-29T17:06:26.59Z","creation":"2026-04-08T05:25:34.351Z"},"accession":"S-EPMC12367329","cross_references":{"pubmed":["39714935"],"doi":["10.1056/evidoa2400223","10.1056/EVIDoa2400223"]}}