{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Sawka AM"],"pubmed_abstract":["<h4>Importance</h4>In managing early-stage cancers, active surveillance (AS) may be preferentially favored by older individuals. In counseling patients, it is important to understand the durability of AS in the context of age.<h4>Objective</h4>To evaluate the durability of AS in patients with small, low-risk papillary thyroid cancer (PTC) according to age at the time of choosing AS.<h4>Design, setting, and participants</h4>This single-center, prospective, long-term follow-up cohort study was conducted at a tertiary care hospital in Toronto, Ontario, Canada. Adult patients with small, localized, low-risk PTC less than 2 cm in maximal diameter were enrolled between May 2016 and February 2021. The clinical outcome data were analyzed up to the time point of May 25, 2025, and final data analysi"],"journal":["JAMA surgery"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12368792"],"repository":["biostudies-literature"],"pubmed_title":["Long-Term Durability of Active Surveillance of Small, Low-Risk Papillary Thyroid Cancer."],"pmcid":["PMC12368792"],"pubmed_authors":["Shah M","Higgins K","Hay M","Gooden E","Su J","Devon K","Solomon P","Witterick I","Jones JM","Gantous A","Halperin IJ","Gilbert R","Esemezie AO","Bindlish V","Eskander A","Pasternak JD","Whiteacre L","Anand S","de Almeida J","Goldstein DP","Lin D","Vescan A","Enepekides D","Tsang RW","Xu W","Nazarali K","Baxter NN","Rotstein L","Canadian Thyroid Cancer Active Surveillance Study Group (Greater Toronto Area)","Bharadwaj V","Irish JC","Ezzat S","Banerjee A","Prudencio J","Sawka AM","Ghai S","Gullane PJ","Hafidh M","Segall L","Korman M","Fernandes V","Chang M","Monteiro E","Madani A","Arruda E","Chung J","Gevorgyan A","Gomez Hernandez K","Anderson J","Zahedi A","Gafni A"],"additional_accession":[]},"is_claimable":false,"name":"Long-Term Durability of Active Surveillance of Small, Low-Risk Papillary Thyroid Cancer.","description":"<h4>Importance</h4>In managing early-stage cancers, active surveillance (AS) may be preferentially favored by older individuals. In counseling patients, it is important to understand the durability of AS in the context of age.<h4>Objective</h4>To evaluate the durability of AS in patients with small, low-risk papillary thyroid cancer (PTC) according to age at the time of choosing AS.<h4>Design, setting, and participants</h4>This single-center, prospective, long-term follow-up cohort study was conducted at a tertiary care hospital in Toronto, Ontario, Canada. Adult patients with small, localized, low-risk PTC less than 2 cm in maximal diameter were enrolled between May 2016 and February 2021. The clinical outcome data were analyzed up to the time point of May 25, 2025, and final data analysi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-29T15:24:56.659Z","creation":"2026-04-08T05:18:43.107Z"},"accession":"S-EPMC12368792","cross_references":{"pubmed":["40833769"],"doi":["10.1001/jamasurg.2025.2957"]}}