{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Muhamad NA"],"pubmed_abstract":["<h4>Background</h4>Naltrexone is an opioid receptor antagonist. Naltrexone is used to block the euphoric and sedative effects of drugs such as heroin, codeine, and morphine. The medication helps to bind and block opioid receptors to decrease opioid cravings. In Malaysia, naltrexone has been used for maintenance treatments for heroin and alcohol since 1996. However, since 2011, naltrexone has been used as an off-label stimulant use disorder (StUD) treatment to achieve abstinence.<h4>Objective</h4>This study aims to determine the abstinence among StUD and non-StUD patients treated and without naltrexone.<h4>Methods</h4>We will conduct a retrospective cohort study on the effect of naltrexone or treatment as usual (TAU) by examining the data for both StUD and non-StUD patients. We will use pat"],"journal":["JMIR research protocols"],"pagination":["e64101"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12371278"],"repository":["biostudies-literature"],"pubmed_title":["Use of Naltrexone for Patients With Stimulant Use Disorder in Malaysia: Protocol for a Retrospective Cohort Study."],"pmcid":["PMC12371278"],"pubmed_authors":["Isa MFM","Moorthi S","Yusoff MZAM","Quan LK","Sainal N","Yahaya AZ","Malhi AS","Abdullah N","Mohd M","Muhamad NA","Yusof HM","Leman FN","Robert R","Ying LH","Mailvaganam J","Aziz MFA","Ali O","Chemi N","Marimuthu R","Ahmad NLA","Jamalluddin NH","Alaga A","Ma'amor NH","Muhamad Rasat MA","Wahid AZA","Misnan NS","Ibrahim N","Terence CE","My Addiction Study group","Tengku Baharudin Shah TPN","Rosli ''"],"additional_accession":[]},"is_claimable":false,"name":"Use of Naltrexone for Patients With Stimulant Use Disorder in Malaysia: Protocol for a Retrospective Cohort Study.","description":"<h4>Background</h4>Naltrexone is an opioid receptor antagonist. Naltrexone is used to block the euphoric and sedative effects of drugs such as heroin, codeine, and morphine. The medication helps to bind and block opioid receptors to decrease opioid cravings. In Malaysia, naltrexone has been used for maintenance treatments for heroin and alcohol since 1996. However, since 2011, naltrexone has been used as an off-label stimulant use disorder (StUD) treatment to achieve abstinence.<h4>Objective</h4>This study aims to determine the abstinence among StUD and non-StUD patients treated and without naltrexone.<h4>Methods</h4>We will conduct a retrospective cohort study on the effect of naltrexone or treatment as usual (TAU) by examining the data for both StUD and non-StUD patients. We will use pat","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-08T10:51:22.489Z","creation":"2026-05-03T03:06:02.481Z"},"accession":"S-EPMC12371278","cross_references":{"pubmed":["40773739"],"doi":["10.2196/64101"]}}