{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hidalgo Mas MDR"],"funding":["Academy of Medical Sciences"],"pagination":["e092226"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12374656"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(8)"],"pubmed_abstract":["A spinal cord injury (SCI) disrupts synaptic connections between the corticospinal tract and motor neurons, impairing muscle control below the injury site. Many individuals with an SCI have impaired trunk control, affecting the performance of activities of daily living and quality of life. Work has shown improvements in trunk control after home-based, unsupervised arm-crank exercise training (ACET) in people with chronic motor-incomplete SCI. However, no studies have examined ACET's impact on trunk control in individuals with subacute SCI. This study aims to investigate ACET's effects on trunk control in adults with subacute incomplete SCI, and its mechanisms, and its long-term benefits on neuropathic pain, psychological well-being, physical activity levels and health-related quality of li"],"journal":["BMJ open"],"pubmed_title":["Self-directed arm-crank exercise to improve volitional control of the trunk in patients with subacute spinal cord injury: a multicentre, parallel-group, randomised controlled trial protocol."],"pmcid":["PMC12374656"],"funding_grant_id":["SBF008\\1116"],"pubmed_authors":["Martinez-Valdes E","Chiu CY","Ahmed Z","Kearney J","Nightingale TE","Duda JL","Chiou SY","Hidalgo Mas MDR","Middleton V"],"additional_accession":[]},"is_claimable":false,"name":"Self-directed arm-crank exercise to improve volitional control of the trunk in patients with subacute spinal cord injury: a multicentre, parallel-group, randomised controlled trial protocol.","description":"A spinal cord injury (SCI) disrupts synaptic connections between the corticospinal tract and motor neurons, impairing muscle control below the injury site. Many individuals with an SCI have impaired trunk control, affecting the performance of activities of daily living and quality of life. Work has shown improvements in trunk control after home-based, unsupervised arm-crank exercise training (ACET) in people with chronic motor-incomplete SCI. However, no studies have examined ACET's impact on trunk control in individuals with subacute SCI. This study aims to investigate ACET's effects on trunk control in adults with subacute incomplete SCI, and its mechanisms, and its long-term benefits on neuropathic pain, psychological well-being, physical activity levels and health-related quality of li","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-08T06:53:31.983Z","creation":"2026-04-07T23:31:26.347Z"},"accession":"S-EPMC12374656","cross_references":{"pubmed":["40840986"],"doi":["10.1136/bmjopen-2024-092226"]}}