{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang J"],"funding":["Shandong Provincial Medical and Health Technology Program","Shandong Provincial Natural Science Foundation","the National Natural Science Foundation of China"],"pagination":["31065"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12375064"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(1)"],"pubmed_abstract":["This prospective study aimed to investigate changes in corneal higher-order aberrations (HOAs) in myopic children using orthokeratology (ortho-k) lenses and their relationship with myopia progression. A total of 112 children aged 8-13 years were divided into group A (axial elongation ≤ 0.1 mm/y with ortho-k) and group B (axial elongation > 0.1 mm/y with ortho-k). At baseline, 1, 6, and 12 months following the initiation of lens wear, HOAs and corneal peripheral defocus were evaluated. Ninety-three patients completed the 1-year follow-up. The mean axial elongation was - 0.07 ± 0.15 mm/y in group A, versus 0.32 ± 0.17 mm/y in group B. No statistical differences were observed in HOAs and corneal peripheral defocus at 1, 6, and 12 months (F = 0.653, 0.878; P > 0.05). Multivariate linear regres"],"journal":["Scientific reports"],"pubmed_title":["Corneal higher-order aberrations as key predictive indicators of axial elongation in myopic children with orthokeratology: a single-center prospective cohort study."],"pmcid":["PMC12375064"],"funding_grant_id":["ZR2019ZD37","82271052, U20A20386","202307021429"],"pubmed_authors":["Ding R","Zhu Z","Zhang J","Zhang X","Wang T","Shi W","Ji Y","Bao Q"],"additional_accession":[]},"is_claimable":false,"name":"Corneal higher-order aberrations as key predictive indicators of axial elongation in myopic children with orthokeratology: a single-center prospective cohort study.","description":"This prospective study aimed to investigate changes in corneal higher-order aberrations (HOAs) in myopic children using orthokeratology (ortho-k) lenses and their relationship with myopia progression. A total of 112 children aged 8-13 years were divided into group A (axial elongation ≤ 0.1 mm/y with ortho-k) and group B (axial elongation > 0.1 mm/y with ortho-k). At baseline, 1, 6, and 12 months following the initiation of lens wear, HOAs and corneal peripheral defocus were evaluated. Ninety-three patients completed the 1-year follow-up. The mean axial elongation was - 0.07 ± 0.15 mm/y in group A, versus 0.32 ± 0.17 mm/y in group B. No statistical differences were observed in HOAs and corneal peripheral defocus at 1, 6, and 12 months (F = 0.653, 0.878; P > 0.05). Multivariate linear regres","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-10T04:21:32.76Z","creation":"2026-04-08T01:28:47.054Z"},"accession":"S-EPMC12375064","cross_references":{"pubmed":["40849596"],"doi":["10.1038/s41598-025-17115-w"]}}