{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(1)"],"submitter":["Bougioukas L"],"pubmed_abstract":["Lye ingestion or other esophageal trauma may require surgical reconstruction. The hypopharyngeal anastomosis during esophageal reconstruction is a technically demanding procedure with many nuances in approach. Patients often have a challenging post-operative course, and few regain the ability to tolerate a normal diet. We describe a case series of three patients (2 colon interpositions and 1 gastric pull-up) who underwent esophageal reconstruction with a hypopharyngeal anastomosis at our institution from years 2017 to 2024, then review the literature. We recommend a multidisciplinary team approach with otolaryngology and/or general surgery for the neck dissection and preparation of the conduit. For the hypopharyngeal anastomosis, we recommend a two-layer, interrupted suture method to the left, lateral piriform sinus along with careful laryngeal nerve preservation. Patients require close follow-up for endoscopic therapy to treat the often-inevitable dysphagia after surgery. All three patients survived and had improved swallow function after surgery."],"journal":["Journal of cardiothoracic surgery"],"pagination":["345"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12379545"],"repository":["biostudies-literature"],"pubmed_title":["Esophageal reconstruction using a hypopharyngeal anastomosis - a single center experience with review of the literature."],"pmcid":["PMC12379545"],"pubmed_authors":["Zeltsman D","Weiss MJ","Jurado JE","Hyman KM","Lee PC","Glassman LR","Bougioukas L","Pereira LM"],"additional_accession":[]},"is_claimable":false,"name":"Esophageal reconstruction using a hypopharyngeal anastomosis - a single center experience with review of the literature.","description":"Lye ingestion or other esophageal trauma may require surgical reconstruction. The hypopharyngeal anastomosis during esophageal reconstruction is a technically demanding procedure with many nuances in approach. Patients often have a challenging post-operative course, and few regain the ability to tolerate a normal diet. We describe a case series of three patients (2 colon interpositions and 1 gastric pull-up) who underwent esophageal reconstruction with a hypopharyngeal anastomosis at our institution from years 2017 to 2024, then review the literature. We recommend a multidisciplinary team approach with otolaryngology and/or general surgery for the neck dissection and preparation of the conduit. For the hypopharyngeal anastomosis, we recommend a two-layer, interrupted suture method to the left, lateral piriform sinus along with careful laryngeal nerve preservation. Patients require close follow-up for endoscopic therapy to treat the often-inevitable dysphagia after surgery. All three patients survived and had improved swallow function after surgery.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-28T02:19:35.082Z","creation":"2026-04-08T02:07:43.39Z"},"accession":"S-EPMC12379545","cross_references":{"pubmed":["40859374"],"doi":["10.1186/s13019-025-03575-8"]}}