{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["173(3)"],"submitter":["Jellema M"],"pubmed_abstract":["<h4>Objective</h4>This study evaluated outcomes of stapes surgery in otosclerosis patients by assessing audiometric results and health-related quality of life (HRQOL) using the Dutch Stapesplasty Outcome Test-25 (SPOT-25) questionnaire. Additionally, the role of SPOT-25 in preoperative decision-making and as a follow-up tool was explored.<h4>Study design</h4>A prospective, multicenter cohort study.<h4>Setting</h4>One tertiary academic medical center and 3 secondary referral centers.<h4>Methods</h4>Data from 115 adult patients undergoing primary stapes surgery was analyzed. Audiometric outcomes were measured using pure-tone audiometry results and word recognition score (WRS). HRQOL was assessed using SPOT-25, Glasgow Health Status Questionnaire, and Glasgow Benefit Inventory. Pre- and postoperative outcomes were compared, and correlations between pure-tone audiometry results, WRS, and HRQOL were analyzed. Outcomes were compared between patients receiving 0.4 and 0.6 mm diameter pistons, and the impact of preoperative pure-tone audiometry results was analyzed.<h4>Results</h4>Significant postoperative improvements were observed in all audiometric measures (mean air conduction gain of 22 dB and air-bone gap (ABG) improvement of 18 dB). HRQOL also improved significantly (mean SPOT-25 score improved from 48 to 27). The 0.6 mm piston group had a significantly smaller postoperative ABG than the 0.4 mm group. Patients with a preoperative ABG ≤ 15 dB had a mean SPOT-25 gain of 19 (SD 22), whereas those with a preoperative ABG > 15 dB had a gain of 21 (SD 18).<h4>Conclusion</h4>Stapes surgery significantly improves hearing and HRQOL. The SPOT-25 is a valuable tool for evaluating HRQOL and may assist in preoperative decision-making in patients with varying hearing impairments.<h4>Level of evidence</h4>III."],"journal":["Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery"],"pagination":["697-704"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12379838"],"repository":["biostudies-literature"],"pubmed_title":["Patient's Perspective and Change in Quality of Life After Stapes Surgery: A Multicenter Prospective Trial."],"pmcid":["PMC12379838"],"pubmed_authors":["Stokroos RJ","Thomeer HGXM","Jellema M","Wegner I","van Waegeningh HF","Blijleven EE","Hemler RJB","Buwalda J"],"additional_accession":[]},"is_claimable":false,"name":"Patient's Perspective and Change in Quality of Life After Stapes Surgery: A Multicenter Prospective Trial.","description":"<h4>Objective</h4>This study evaluated outcomes of stapes surgery in otosclerosis patients by assessing audiometric results and health-related quality of life (HRQOL) using the Dutch Stapesplasty Outcome Test-25 (SPOT-25) questionnaire. Additionally, the role of SPOT-25 in preoperative decision-making and as a follow-up tool was explored.<h4>Study design</h4>A prospective, multicenter cohort study.<h4>Setting</h4>One tertiary academic medical center and 3 secondary referral centers.<h4>Methods</h4>Data from 115 adult patients undergoing primary stapes surgery was analyzed. Audiometric outcomes were measured using pure-tone audiometry results and word recognition score (WRS). HRQOL was assessed using SPOT-25, Glasgow Health Status Questionnaire, and Glasgow Benefit Inventory. Pre- and postoperative outcomes were compared, and correlations between pure-tone audiometry results, WRS, and HRQOL were analyzed. Outcomes were compared between patients receiving 0.4 and 0.6 mm diameter pistons, and the impact of preoperative pure-tone audiometry results was analyzed.<h4>Results</h4>Significant postoperative improvements were observed in all audiometric measures (mean air conduction gain of 22 dB and air-bone gap (ABG) improvement of 18 dB). HRQOL also improved significantly (mean SPOT-25 score improved from 48 to 27). The 0.6 mm piston group had a significantly smaller postoperative ABG than the 0.4 mm group. Patients with a preoperative ABG ≤ 15 dB had a mean SPOT-25 gain of 19 (SD 22), whereas those with a preoperative ABG > 15 dB had a gain of 21 (SD 18).<h4>Conclusion</h4>Stapes surgery significantly improves hearing and HRQOL. The SPOT-25 is a valuable tool for evaluating HRQOL and may assist in preoperative decision-making in patients with varying hearing impairments.<h4>Level of evidence</h4>III.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-10T01:51:29.238Z","creation":"2026-04-08T01:25:41.84Z"},"accession":"S-EPMC12379838","cross_references":{"pubmed":["40344441"],"doi":["10.1002/ohn.1298"]}}