biostudies-literatureUnknown23(3)Wang 王晨 CSelf-incompatibility (SI) is an important genetic mechanism in angiosperms that prevents inbreeding and promotes outcrossing, with significant implications for crop breeding, including genetic diversity, hybrid seed production, and yield optimization. In eudicots, SI is typically governed by a single S-locus containing tightly linked pistil and pollen S-determinant genes. Despite major advances in SI research, a centralized, comprehensive resource for SI-related genomic data remains lacking. To address this gap, we developed the Plant Self-Incompatibility Atlas (PSIA), a systematically curated knowledgebase providing an extensive compilation of plant SI, including genomic resources for SI species, S gene annotations, molecular mechanisms, phylogenetic relationships, and comparative genomicGenomics, proteomics & bioinformaticsqzaf046https://www.ebi.ac.uk/biostudies/studies/S-EPMC12396629biostudies-literaturePSIA: A Comprehensive Knowledgebase of Plant Self-incompatibility.PMC12396629Wang 王晨 CZhang 张洪魁 HSun 孙思杰 SZhao 赵洪 HXue 薛勇彪 YfalsePSIA: A Comprehensive Knowledgebase of Plant Self-incompatibility.Self-incompatibility (SI) is an important genetic mechanism in angiosperms that prevents inbreeding and promotes outcrossing, with significant implications for crop breeding, including genetic diversity, hybrid seed production, and yield optimization. In eudicots, SI is typically governed by a single S-locus containing tightly linked pistil and pollen S-determinant genes. Despite major advances in SI research, a centralized, comprehensive resource for SI-related genomic data remains lacking. To address this gap, we developed the Plant Self-Incompatibility Atlas (PSIA), a systematically curated knowledgebase providing an extensive compilation of plant SI, including genomic resources for SI species, S gene annotations, molecular mechanisms, phylogenetic relationships, and comparative genomic2025-01-01T00:00:00Z2025 Jul2026-04-08T11:16:16.194Z2026-04-08T01:51:00.069ZS-EPMC123966294039748010.1093/gpbjnl/qzaf046