biostudies-literatureUnknown13Cheng Q<h4>Background</h4>Pneumoconiosis remains one of the most critical occupational health hazards globally. Utilizing data from the Global Burden of Disease (GBD) 2021, we have updated the epidemiological trends of pneumoconiosis.<h4>Methods</h4>We conducted and analyzed pneumoconiosis-related data from the GBD 2021 study for individuals aged ≥20 years. Our analysis described the incident cases and age-standardized incidence rates (ASIRs) across various global regions and age groups. Temporal trends were evaluated using Estimated Annual Percentage Change (EAPC) for ASIRs between 1990 and 2021.<h4>Results</h4>The ASIR of pneumoconiosis among individuals aged ≥20 years declined globally at an annual average of 0.48% between 1990 and 2021. Except for high socio-demographic index (SDI) regions, tFrontiers in public health1608109https://www.ebi.ac.uk/biostudies/studies/S-EPMC12400962biostudies-literatureGlobal, regional, and national trends in the incidence of pneumoconiosis among populations aged 20 and above from 1990 to 2021.PMC12400962Li HHe SHu YCheng QWang SHu XPan PLiao SfalseGlobal, regional, and national trends in the incidence of pneumoconiosis among populations aged 20 and above from 1990 to 2021.<h4>Background</h4>Pneumoconiosis remains one of the most critical occupational health hazards globally. Utilizing data from the Global Burden of Disease (GBD) 2021, we have updated the epidemiological trends of pneumoconiosis.<h4>Methods</h4>We conducted and analyzed pneumoconiosis-related data from the GBD 2021 study for individuals aged ≥20 years. Our analysis described the incident cases and age-standardized incidence rates (ASIRs) across various global regions and age groups. Temporal trends were evaluated using Estimated Annual Percentage Change (EAPC) for ASIRs between 1990 and 2021.<h4>Results</h4>The ASIR of pneumoconiosis among individuals aged ≥20 years declined globally at an annual average of 0.48% between 1990 and 2021. Except for high socio-demographic index (SDI) regions, t2025-01-01T00:00:00Z20252026-05-29T14:27:49.927Z2026-04-08T05:02:46.924ZS-EPMC124009624090070710.3389/fpubh.2025.1608109