{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Nie C"],"pubmed_abstract":["Q fever, caused by <i>Coxiella burnetii</i> (Q fever <i>rickettsiae</i>), is a zoonotic disease with a natural reservoir and has been reported in many countries and regions. Its clinical presentation is non-specific and easily confused with other infectious or non-infectious diseases. Conventional diagnostic methods, such as respiratory specimen culture, often fail to yield conclusive results, increasing the risk of misdiagnosis. This case involves a 78-year-old male patient from Zhejiang Province, China, who presented with fever as the primary complaint and developed severe pneumonia. The diagnosis of H1N1 influenza co-infection with Coxiella burnetii was confirmed by bronchoalveolar lavage fluid targeted high-throughput sequencing (tNGS). Following antiviral treatment with Maraviroc and "],"journal":["Frontiers in medicine"],"pagination":["1626115"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12401012"],"repository":["biostudies-literature"],"pubmed_title":["Omadacycline in the treatment of severe Q fever pneumonia during an influenza epidemic: a case report with literature review."],"pmcid":["PMC12401012"],"pubmed_authors":["Nie C","Hu S","Yu M","Zhu Y","Qian F","Jiang Q","Zhu X","Zhong X","Zhou H","Zhao X"],"additional_accession":[]},"is_claimable":false,"name":"Omadacycline in the treatment of severe Q fever pneumonia during an influenza epidemic: a case report with literature review.","description":"Q fever, caused by <i>Coxiella burnetii</i> (Q fever <i>rickettsiae</i>), is a zoonotic disease with a natural reservoir and has been reported in many countries and regions. Its clinical presentation is non-specific and easily confused with other infectious or non-infectious diseases. Conventional diagnostic methods, such as respiratory specimen culture, often fail to yield conclusive results, increasing the risk of misdiagnosis. This case involves a 78-year-old male patient from Zhejiang Province, China, who presented with fever as the primary complaint and developed severe pneumonia. The diagnosis of H1N1 influenza co-infection with Coxiella burnetii was confirmed by bronchoalveolar lavage fluid targeted high-throughput sequencing (tNGS). Following antiviral treatment with Maraviroc and ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-29T22:10:00.996Z","creation":"2026-05-18T03:07:09.743Z"},"accession":"S-EPMC12401012","cross_references":{"pubmed":["40901522"],"doi":["10.3389/fmed.2025.1626115"]}}