{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Crump C"],"funding":["the National Institutes of Health","Avtal om Läkarutbildning och Forskning","Avtal om Läkarutbildning och Forskning (ALF; Agreement on Medical Training and Research)","the Swedish Heart-Lung Foundation","NHLBI NIH HHS","the Swedish Research Council","National Institutes of Health","Swedish Research Council","NIH HHS","Swedish Heart-Lung Foundation"],"pagination":["3290-3300"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12401571"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["46(33)"],"pubmed_abstract":["<h4>Background and aims</h4>The lifelong risk of stroke following adverse pregnancy outcomes, and potential causality, are unknown. This study examined five major adverse pregnancy outcomes and long-term risk of stroke in a large population-based cohort.<h4>Methods</h4>A national cohort study was conducted of all 2 201 393 women with a singleton delivery in Sweden during 1973-2015, followed up for stroke through 2018. Cox regression was used to determine hazard ratios (HRs) for stroke associated with preterm delivery, small for gestational age, preeclampsia, other hypertensive disorders, and gestational diabetes, adjusting for other maternal factors. Co-sibling analyses assessed for potential confounding by shared familial (genetic or environmental) factors.<h4>Results</h4>In 48 million pe"],"journal":["European heart journal"],"pubmed_title":["Adverse pregnancy outcomes and long-term risk of stroke: a Swedish nationwide co-sibling study."],"pmcid":["PMC12401571"],"funding_grant_id":["R01 HL139536","R01HL139536"],"pubmed_authors":["Sundquist J","Crump C","Sundquist K"],"additional_accession":[]},"is_claimable":false,"name":"Adverse pregnancy outcomes and long-term risk of stroke: a Swedish nationwide co-sibling study.","description":"<h4>Background and aims</h4>The lifelong risk of stroke following adverse pregnancy outcomes, and potential causality, are unknown. This study examined five major adverse pregnancy outcomes and long-term risk of stroke in a large population-based cohort.<h4>Methods</h4>A national cohort study was conducted of all 2 201 393 women with a singleton delivery in Sweden during 1973-2015, followed up for stroke through 2018. Cox regression was used to determine hazard ratios (HRs) for stroke associated with preterm delivery, small for gestational age, preeclampsia, other hypertensive disorders, and gestational diabetes, adjusting for other maternal factors. Co-sibling analyses assessed for potential confounding by shared familial (genetic or environmental) factors.<h4>Results</h4>In 48 million pe","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-06T11:28:24.823Z","creation":"2026-05-29T03:13:18.086Z"},"accession":"S-EPMC12401571","cross_references":{"pubmed":["40569854"],"doi":["10.1093/eurheartj/ehaf366"]}}