biostudies-literatureUnknown20(9)AlSaleh A<h4>Background</h4>The Saudi Acute Myocardial Infarction Registry (STARS) program aims to evaluate the clinical characteristics, management, and outcomes of a representative sample of patients with acute myocardial infarction (AMI) in Saudi Arabia. This second phase evaluates temporal changes in patient care, demographics, and the management benchmarks for AMI.<h4>Methods and findings</h4>We created a 5-year recurring, multi-center prospective registry that utilizes a snapshot design in 50 hospitals from various healthcare sectors in Saudi Arabia. The study's recruitment phase spanned from September 3, 2021, to January 6, 2023. During these 16 months, 2,690 patients presenting with acute myocardial infarction (AMI) with or without ST-segment elevation (STEMI or NSTEMI, respectively) were ePloS onee0331215https://www.ebi.ac.uk/biostudies/studies/S-EPMC12404464biostudies-literatureThe second survey of the Saudi Acute Myocardial Infarction Registry Program: Main results and temporal changes in care (STARS-2 program).PMC12404464Sayed BAAlbareda HAAlhaj WIIbrahim SMKhoja AYAlsabatien BAttia NMEltayeb AOAlmasswary AAl-Murayeh MAhmed EAl Faraidy KHussain NBasardah ALawand SRSerafi AHussein GAYa'u JAUl-Sabah ZAlali RAlmoghairi AMAlqarawi WAlasnag MBin Ghouth NMAskar TMHamza MKAlharbi IAAwwad AAAlSaleh AKholaif NKinsara AJAlmokhlef AAltaradi HAlhadramy OSTARS-2 InvestigatorsGhabashi AEAlbawardi RBuSaleh AHAl Habeeb MAAlmutairi FAlhabib KFAldossari MAMohamed MAAbdulhabeeb IAMAlshehri MHaider KHAlkutshan RShujauddin SQutub MAAlSaif SMAlsharkawy RAminu BSAli MYoussef MKIKazim HAlasmari SfalseThe second survey of the Saudi Acute Myocardial Infarction Registry Program: Main results and temporal changes in care (STARS-2 program).<h4>Background</h4>The Saudi Acute Myocardial Infarction Registry (STARS) program aims to evaluate the clinical characteristics, management, and outcomes of a representative sample of patients with acute myocardial infarction (AMI) in Saudi Arabia. This second phase evaluates temporal changes in patient care, demographics, and the management benchmarks for AMI.<h4>Methods and findings</h4>We created a 5-year recurring, multi-center prospective registry that utilizes a snapshot design in 50 hospitals from various healthcare sectors in Saudi Arabia. The study's recruitment phase spanned from September 3, 2021, to January 6, 2023. During these 16 months, 2,690 patients presenting with acute myocardial infarction (AMI) with or without ST-segment elevation (STEMI or NSTEMI, respectively) were e2025-01-01T00:00:00Z20252026-05-29T16:59:41.295Z2026-04-08T05:26:30.083ZS-EPMC124044644089277710.1371/journal.pone.0331215