{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shi Z"],"funding":["National Natural Science Foundation of China"],"pagination":["175"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12406380"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(1)"],"pubmed_abstract":["<h4>Objectives</h4>To evaluate the diagnostic accuracy of salivary gland ultrasound (SGUS) in patients with high suspicion of Sjögren's Disease (SjD) and to determine its potential role in the diagnostic process.<h4>Methods</h4>This study is a cross-sectional diagnostic trial based on a prospective cohort, including 171 patients with high suspicion of SjD. SGUS of the parotid glands (PG) and submandibular glands (SMG) was performed according to the OMERACT scoring system. The predictive value of SGUS for diagnostic outcomes and labial salivary gland biopsy (LSGB) results was analyzed. The correlation between SGUS grading and unstimulated salivary flow rates (USFR) was also assessed using statistical tests.<h4>Results</h4>Of the 171 participants, 130 were diagnosed with SjD. The OMERACT tot"],"journal":["Arthritis research & therapy"],"pubmed_title":["The diagnostic value and clinical relevance of salivary gland ultrasound in patients with highly suspected Sjogren's Disease: a prospective monocentric study."],"pmcid":["PMC12406380"],"funding_grant_id":["No. 82104719","No. 82374318"],"pubmed_authors":["Li G","Hou J","Ding Y","Dong X","Xue L","Li B","Shi Z"],"additional_accession":[]},"is_claimable":false,"name":"The diagnostic value and clinical relevance of salivary gland ultrasound in patients with highly suspected Sjogren's Disease: a prospective monocentric study.","description":"<h4>Objectives</h4>To evaluate the diagnostic accuracy of salivary gland ultrasound (SGUS) in patients with high suspicion of Sjögren's Disease (SjD) and to determine its potential role in the diagnostic process.<h4>Methods</h4>This study is a cross-sectional diagnostic trial based on a prospective cohort, including 171 patients with high suspicion of SjD. SGUS of the parotid glands (PG) and submandibular glands (SMG) was performed according to the OMERACT scoring system. The predictive value of SGUS for diagnostic outcomes and labial salivary gland biopsy (LSGB) results was analyzed. The correlation between SGUS grading and unstimulated salivary flow rates (USFR) was also assessed using statistical tests.<h4>Results</h4>Of the 171 participants, 130 were diagnosed with SjD. The OMERACT tot","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-29T21:20:52.841Z","creation":"2026-04-08T06:01:38.432Z"},"accession":"S-EPMC12406380","cross_references":{"pubmed":["40898326"],"doi":["10.1186/s13075-025-03642-4"]}}