biostudies-literatureUnknown40(4)Yu JInstitute of Clinical Medicine Research in the Yeouido St. Mary's Hospital, The Catholic University of KoreaInstitute of Clinical Medicine Research in the Yeouido St. Mary’s Hospital, The Catholic University of Korea<h4>Backgruound</h4>This study aimed to assess whether markers of diabetes severity could serve as predictors for foot amputation risk among patients with type 2 diabetes mellitus.<h4>Methods</h4>We analyzed data from the nationally representative Korean National Health Insurance System database, tracking 2,544,077 patients with type 2 diabetes mellitus who participated in routine health check-ups between 2009 and 2012, with followup extending through the end of 2018. The parameters used to define the diabetes severity score encompassed diabetes duration, insulin usage, the number of oral glucose-lowering medications, the presence of chronic kidney disease, diabetic retinopathy, and cardiovascular disease. Each factor was assigned one point, yielding a cumulative severity score ranging froEndocrinology and metabolism (Seoul, Korea)574-582https://www.ebi.ac.uk/biostudies/studies/S-EPMC12409162biostudies-literatureThe Severity of Diabetes and the Risk of Diabetic Foot Amputation: A National Cohort Study.PMC12409162Kim BHan KLee SHKim JHKim MKYu JfalseThe Severity of Diabetes and the Risk of Diabetic Foot Amputation: A National Cohort Study.<h4>Backgruound</h4>This study aimed to assess whether markers of diabetes severity could serve as predictors for foot amputation risk among patients with type 2 diabetes mellitus.<h4>Methods</h4>We analyzed data from the nationally representative Korean National Health Insurance System database, tracking 2,544,077 patients with type 2 diabetes mellitus who participated in routine health check-ups between 2009 and 2012, with followup extending through the end of 2018. The parameters used to define the diabetes severity score encompassed diabetes duration, insulin usage, the number of oral glucose-lowering medications, the presence of chronic kidney disease, diabetic retinopathy, and cardiovascular disease. Each factor was assigned one point, yielding a cumulative severity score ranging fro2025-01-01T00:00:00Z2025 Aug2026-05-29T20:11:43.646Z2026-04-08T06:00:40.669ZS-EPMC124091624022996810.3803/EnM.2024.2266