{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Heiniger EK"],"funding":["National Institutes of Health"],"pubmed_abstract":["Curable sexually transmitted infections (STIs) caused by the bacteria <i>Chlamydia trachomatis</i> (CT) and <i>Neisseria gonorrhoeae</i> (NG) are widespread globally. These infections are particularly dangerous for female patients, causing pelvic inflammatory disease, infertility, and increased risk of HIV acquisition. Vaginal self-swab sampling can improve access to STI screening but is still subject to treatment delays due to centralized processing. A low-cost point-of-care (POC) device capable of detecting these bacteria from a self- or clinician-collected vaginal swab could address this delay and allow for more timely treatment. In this work, vaginal swab materials from patients infected with CT or NG required a filtration step before lysis and loop-mediated isothermal amplification (L"],"journal":["The Analyst"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12412115"],"repository":["biostudies-literature"],"pubmed_title":["A low-cost point-of-care device for the simultaneous detection of two sexually transmitted bacterial pathogens in vaginal swab samples."],"pmcid":["PMC12412115"],"funding_grant_id":["U54EB007958"],"pubmed_authors":["Jiang KP","Yager P","Heiniger EK","Kumar S"],"additional_accession":[]},"is_claimable":false,"name":"A low-cost point-of-care device for the simultaneous detection of two sexually transmitted bacterial pathogens in vaginal swab samples.","description":"Curable sexually transmitted infections (STIs) caused by the bacteria <i>Chlamydia trachomatis</i> (CT) and <i>Neisseria gonorrhoeae</i> (NG) are widespread globally. These infections are particularly dangerous for female patients, causing pelvic inflammatory disease, infertility, and increased risk of HIV acquisition. Vaginal self-swab sampling can improve access to STI screening but is still subject to treatment delays due to centralized processing. A low-cost point-of-care (POC) device capable of detecting these bacteria from a self- or clinician-collected vaginal swab could address this delay and allow for more timely treatment. In this work, vaginal swab materials from patients infected with CT or NG required a filtration step before lysis and loop-mediated isothermal amplification (L","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-29T21:42:49.634Z","creation":"2026-04-08T06:05:30.326Z"},"accession":"S-EPMC12412115","cross_references":{"pubmed":["40910374"],"doi":["10.1039/d5an00496a"]}}