{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shahidul Islam S"],"funding":["Japan Society for the Promotion of Science"],"pagination":["32143-32154"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12412208"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(39)"],"pubmed_abstract":["The application of nanoscale metal-organic frameworks (MOFs) in tissue engineering is receiving increased attention. As three-dimensional scaffolding materials that provide an appropriate extracellular microenvironment supporting the survival, proliferation, and organization of cells play a key role <i>in vivo</i> tissue engineering, hybridization of nanoscale MOFs with bulk hydrogels has led to the development of nanoscale MOF-combined hydrogels. However, development of nanoscale MOF-combined hydrogel scaffolds remains challenging. Generally, since the gelation properties of injectable hydrogels are delicate, the sol-gel transition behavior could be lost due to the influence of additives. To date, little progress has been made in the development of nanoscale MOF-combined injectable hydrog"],"journal":["RSC advances"],"pubmed_title":["Metal-organic framework-injectable hydrogel hybrid scaffolds promote accelerated angiogenesis for &lt;i&gt;in vivo&lt;/i&gt; tissue engineering."],"pmcid":["PMC12412208"],"funding_grant_id":["KAKENHI 22K19925"],"pubmed_authors":["Nagahama K","Shahidul Islam S","Dode T","Fukuoka M","Tsuruoka T","Kawashima S"],"additional_accession":[]},"is_claimable":false,"name":"Metal-organic framework-injectable hydrogel hybrid scaffolds promote accelerated angiogenesis for &lt;i&gt;in vivo&lt;/i&gt; tissue engineering.","description":"The application of nanoscale metal-organic frameworks (MOFs) in tissue engineering is receiving increased attention. As three-dimensional scaffolding materials that provide an appropriate extracellular microenvironment supporting the survival, proliferation, and organization of cells play a key role <i>in vivo</i> tissue engineering, hybridization of nanoscale MOFs with bulk hydrogels has led to the development of nanoscale MOF-combined hydrogels. However, development of nanoscale MOF-combined hydrogel scaffolds remains challenging. Generally, since the gelation properties of injectable hydrogels are delicate, the sol-gel transition behavior could be lost due to the influence of additives. To date, little progress has been made in the development of nanoscale MOF-combined injectable hydrog","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-01T13:50:27.249Z","creation":"2026-04-08T13:15:31.103Z"},"accession":"S-EPMC12412208","cross_references":{"pubmed":["40918318"],"doi":["10.1039/d5ra02770e"]}}