{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["106(3)"],"submitter":["O'Callaghan D"],"funding":["The authors received no specific funding for this work."],"pubmed_abstract":["Background
In patients with de novo coronary artery disease (CAD), percutaneous coronary intervention (PCI) with drug eluting stent (DES) implantation is the gold standard therapy. New evidence is available with drug coated balloons (DCB) angioplasty. The objective of this meta-analysis was to compare the efficacy and safety of DCB angioplasty versus DES-based PCI for patients with de novo CAD.Methods
A systematic search of PubMed, Scopus, Web of Science, and EMBASE databases was performed from January 1, 2006 up until November 1, 2024. Inclusion criteria were random treatment assignment; PCI with DCB versus DES; patients with de novo CAD; clinical follow-up available for ≥1 year; and studies published in a peer-reviewed journal. Trial-level incidence rate ratios (IRR) with"],"journal":["Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions"],"pagination":["1843-1853"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12412355"],"repository":["biostudies-literature"],"pubmed_title":["Drug Coated Balloons Versus Drug-Eluting Stents in Patients With De Novo Coronary Artery Disease."],"pmcid":["PMC12412355"],"pubmed_authors":["Rai H","Durand R","Blake GJ","Alfonso F","Paradies V","Byrne RA","Colleran R","Giacoppo D","Coughlan JJ","O'Callaghan D"],"additional_accession":[]},"is_claimable":false,"name":"Drug Coated Balloons Versus Drug-Eluting Stents in Patients With De Novo Coronary Artery Disease.","description":"Background
In patients with de novo coronary artery disease (CAD), percutaneous coronary intervention (PCI) with drug eluting stent (DES) implantation is the gold standard therapy. New evidence is available with drug coated balloons (DCB) angioplasty. The objective of this meta-analysis was to compare the efficacy and safety of DCB angioplasty versus DES-based PCI for patients with de novo CAD.Methods
A systematic search of PubMed, Scopus, Web of Science, and EMBASE databases was performed from January 1, 2006 up until November 1, 2024. Inclusion criteria were random treatment assignment; PCI with DCB versus DES; patients with de novo CAD; clinical follow-up available for ≥1 year; and studies published in a peer-reviewed journal. Trial-level incidence rate ratios (IRR) with","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-01T07:56:02.004Z","creation":"2026-04-08T10:43:28.607Z"},"accession":"S-EPMC12412355","cross_references":{"pubmed":["40662340"],"doi":["10.1002/ccd.70005"]}}