{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Schade AT"],"funding":["Wellcome Trust"],"pagination":["e0331569"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12413004"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(9)"],"pubmed_abstract":["<h4>Background</h4>Open tibia fractures result in substantial lifelong disability for patients, and are expensive to treat. As the injury typically affects young working men, the societal costs from open tibia fractures are likely to also be high in low income countries, but remain largely unknown. We therefore investigated the overall societal costs and cost-effectiveness of different orthopaedic treatments at one year following an open tibia fracture in Malawi.<h4>Methods</h4>This study was a cost-utility analysis nested in a prospective cohort study from the healthcare- and societal-payer perspectives with a one-year time horizon. We obtained quality-adjusted life years (QALYs) from the EuroQoL 5 Dimension 3 Level (EQ-5D-3L) and patient lost productivity estimates at 6 weeks, and 3, 6, "],"journal":["PloS one"],"pubmed_title":["Economic burden and cost-effectiveness of treatments for open tibia fractures in Malawi: Economic analysis of a multicentre prospective cohort study."],"pmcid":["PMC12413004"],"funding_grant_id":["203919"],"pubmed_authors":["Lalloo DG","Sabawo M","Metcalfe AJ","Sande LA","Madan JJ","Ngoie LB","Tomeny E","Nohakhelha N","Schade AT","Harrison WJ","MacPherson P","Mwafulirwa K"],"additional_accession":[]},"is_claimable":false,"name":"Economic burden and cost-effectiveness of treatments for open tibia fractures in Malawi: Economic analysis of a multicentre prospective cohort study.","description":"<h4>Background</h4>Open tibia fractures result in substantial lifelong disability for patients, and are expensive to treat. As the injury typically affects young working men, the societal costs from open tibia fractures are likely to also be high in low income countries, but remain largely unknown. We therefore investigated the overall societal costs and cost-effectiveness of different orthopaedic treatments at one year following an open tibia fracture in Malawi.<h4>Methods</h4>This study was a cost-utility analysis nested in a prospective cohort study from the healthcare- and societal-payer perspectives with a one-year time horizon. We obtained quality-adjusted life years (QALYs) from the EuroQoL 5 Dimension 3 Level (EQ-5D-3L) and patient lost productivity estimates at 6 weeks, and 3, 6, ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-29T22:38:35.826Z","creation":"2026-04-08T06:17:53.712Z"},"accession":"S-EPMC12413004","cross_references":{"pubmed":["40911543"],"doi":["10.1371/journal.pone.0331569"]}}