biostudies-literatureUnknown3(3)Phillips EM<h4>Objective</h4>This study examined associations between actigraphy-derived sleep metrics (ie, intraindividual sleep variability, average sleep duration, bedtime, and waketime) and psychopathology to discern their roles as potential transdiagnostic factors related to psychiatric problems during adolescence.<h4>Method</h4>In a sample of 238 adolescents (aged 14-18 years; 0.4% Asian American, 4.0% Black, 22.0% Multiracial, and 73.5% White; 53.4% female) oversampled for socioeconomic risk, we used a bifactor s-1 model of psychopathology, with emotion dysregulation as the reference indicator, to model the general factor of dysregulation and psychopathology (GF-DP) as well as specific internalizing and externalizing factors. We used multilevel structural equation modeling with the Markov chaiJAACAP open701-712https://www.ebi.ac.uk/biostudies/studies/S-EPMC12414309biostudies-literatureAdolescent Sleep as a Transdiagnostic Factor: Associations Between Actigraphy-Derived Night-to-Night Sleep Metrics and Adolescent Psychopathology.PMC12414309Brock RLEspy KAGoldberg ELPhillips EMHamburger ERNelson JMMason WANelson TDfalseAdolescent Sleep as a Transdiagnostic Factor: Associations Between Actigraphy-Derived Night-to-Night Sleep Metrics and Adolescent Psychopathology.<h4>Objective</h4>This study examined associations between actigraphy-derived sleep metrics (ie, intraindividual sleep variability, average sleep duration, bedtime, and waketime) and psychopathology to discern their roles as potential transdiagnostic factors related to psychiatric problems during adolescence.<h4>Method</h4>In a sample of 238 adolescents (aged 14-18 years; 0.4% Asian American, 4.0% Black, 22.0% Multiracial, and 73.5% White; 53.4% female) oversampled for socioeconomic risk, we used a bifactor s-1 model of psychopathology, with emotion dysregulation as the reference indicator, to model the general factor of dysregulation and psychopathology (GF-DP) as well as specific internalizing and externalizing factors. We used multilevel structural equation modeling with the Markov chai2025-01-01T00:00:00Z2025 Sep2026-06-02T22:35:54.131Z2026-05-28T03:06:53.255ZS-EPMC124143094092279610.1016/j.jaacop.2024.06.001