biostudies-literatureUnknown15Lee YJ<h4>Introduction</h4>Breast cancer (BC) treatments can impair fertility in young women, causing considerable distress and potentially influencing treatment decisions, yet comprehensive real-world data on pregnancy outcomes after BC remain limited. This study aims to provide comprehensive real-world data on pregnancy following BC treatment to guide clinical practice and patient counseling.<h4>Methods</h4>We conducted a retrospective cohort study using medical records from a single tertiary medical center in South Korea. The study included 995 premenopausal women aged 18 to 40 years who were diagnosed with stage 0-III BC between December 2010 and September 2020. The primary outcomes included post-treatment pregnancy rates, factors associated with subsequent pregnancy, timing of conception, pFrontiers in oncology1656429https://www.ebi.ac.uk/biostudies/studies/S-EPMC12414922biostudies-literaturePregnancy after breast cancer treatment in young patients.PMC12414922Yoo TKKim SSon BHKim HJLee YJKim JChung IYLee SBKo BSLee JWfalsePregnancy after breast cancer treatment in young patients.<h4>Introduction</h4>Breast cancer (BC) treatments can impair fertility in young women, causing considerable distress and potentially influencing treatment decisions, yet comprehensive real-world data on pregnancy outcomes after BC remain limited. This study aims to provide comprehensive real-world data on pregnancy following BC treatment to guide clinical practice and patient counseling.<h4>Methods</h4>We conducted a retrospective cohort study using medical records from a single tertiary medical center in South Korea. The study included 995 premenopausal women aged 18 to 40 years who were diagnosed with stage 0-III BC between December 2010 and September 2020. The primary outcomes included post-treatment pregnancy rates, factors associated with subsequent pregnancy, timing of conception, p2025-01-01T00:00:00Z20252026-06-01T16:08:45.082Z2026-04-08T14:04:04.408ZS-EPMC124149224092752110.3389/fonc.2025.1656429