{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["More KD"],"funding":["Agence Nationale de la Recherche (ANR)","Vetenskapsrådet","Agence Nationale de la Recherche","Knut and Alice Wallenberg Foundation","Knut och Alice Wallenbergs Stiftelse","Swedish Research Council","Fondo Social Europeo and Agencia Estatal de Investigación","Science for Life Laboratory","Centro Nacional de Investigación sobre la Evolución Humana","CNRS Zone Atelier PYGAR","European Research Council","Centre National de la Recherche Scientifique","Junta de Comunidades de Castilla la Mancha","H2020 Marie Skłodowska-Curie Actions","Université de Toulouse"],"pagination":["e14112"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12415940"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(7)"],"pubmed_abstract":["In the last three decades, DNA sequencing of ancient animal osteological assemblages has become an important tool complementing standard archaeozoological approaches to reconstruct the history of animal domestication. However, osteological assemblages of key archaeological contexts are not always available or do not necessarily preserve enough ancient DNA for a cost-effective genetic analysis. Here, we develop an in-solution target-enrichment approach, based on 80-mer species-specific RNA probes (ranging from 306 to 1686 per species) to characterise (in single experiments) the mitochondrial genetic variation from eight domesticated animal species of major economic interest: cattle, chickens, dogs, donkeys, goats, horses, pigs and sheep. We also illustrate how our design can be adapted to e"],"journal":["Molecular ecology resources"],"pubmed_title":["Validating a Target-Enrichment Design for Capturing Uniparental Haplotypes in Ancient Domesticated Animals."],"pmcid":["PMC12415940"],"funding_grant_id":["SBPLY/24/180801/000019","CENIEH","897931‐PALEOS","SciLifeLab","101071707","101062645-ZEPHYRUS","CAGT","101062645‐ZEPHYRUS","2021-00625","895107‐ARAUCANA","AnimalFarmIRP","101032990‐PALEOQINOA","RYC2020-029656-I","101117101","895107-ARAUCANA","949330","CoproDNA","ANR‐17‐CE27‐0004","2021‐00625","101032990-PALEOQINOA","MCIN/AEI/10.13039/501100011033","ANR-17-CE27-0004","101054984","897931-PALEOS","681605"],"pubmed_authors":["Allccarima-Crisostomo D","Taylor W","Daly KG","Charliquart L","Chauvey L","Dobrescu R","Castel JC","Tonasso-Calviere L","Charlton S","Garrido JL","Berthon R","Seguin-Orlando A","Vila E","Moskal-Del Hoyo M","Tressieres G","Boudadi-Maligne M","Zhumatayev R","Kosintsev P","Balasescu A","Star B","Mullin VE","Frantz L","Mashkour M","Khazaeli R","Vahdati AA","Rodsrud CL","Burgos NS","Bertani S","Houle JL","Post-Melbye JR","Benecke N","Arbuckle B","Sikanjic PR","Fernandez PM","Schiavinato S","Nowak M","Wilczynski J","Contreras-Mancilla J","Nikgoftar A","Dalen L","Fhon M","Gibert M","McMahon G","Pablos A","Padula H","Vukicevic TT","Buric M","de Noblet T","Alvarez N","Orlando L","Bayarsaikhan J","Shakenov S","Chiavazza H","Lebrasseur O","Bradley DG","Stanton DWG","Barrey E","Steadman S","Guardia NM","Robbe E","Discamps E","Borges C","More KD","Larson G","Estrada O"],"additional_accession":[]},"is_claimable":false,"name":"Validating a Target-Enrichment Design for Capturing Uniparental Haplotypes in Ancient Domesticated Animals.","description":"In the last three decades, DNA sequencing of ancient animal osteological assemblages has become an important tool complementing standard archaeozoological approaches to reconstruct the history of animal domestication. However, osteological assemblages of key archaeological contexts are not always available or do not necessarily preserve enough ancient DNA for a cost-effective genetic analysis. Here, we develop an in-solution target-enrichment approach, based on 80-mer species-specific RNA probes (ranging from 306 to 1686 per species) to characterise (in single experiments) the mitochondrial genetic variation from eight domesticated animal species of major economic interest: cattle, chickens, dogs, donkeys, goats, horses, pigs and sheep. We also illustrate how our design can be adapted to e","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-01T16:09:32.482Z","creation":"2026-04-08T14:04:31.641Z"},"accession":"S-EPMC12415940","cross_references":{"pubmed":["40202701"],"doi":["10.1111/1755-0998.14112"]}}