biostudies-literatureToner ERNIMH NIH HHS2428-2439https://www.ebi.ac.uk/biostudies/studies/S-EPMC12416631biostudies-literatureUnknown16(3)Correctly identifying an individual's social context from passively worn sensors holds promise for delivering just-in-time adaptive interventions (JITAIs) to treat social anxiety. In this study, we present results using passively collected data from a within-subjects experiment that assessed physiological responses across different social contexts (i.e., alone vs. with others), social phases (i.e., pre- and post-interaction vs. during an interaction), social interaction sizes (i.e., dyadic vs. group interactions), and levels of social threat (i.e., implicit vs. explicit social evaluation). Participants in the study (<i>N</i> = 46) reported moderate to severe social anxiety symptoms as assessed by the Social Interaction Anxiety Scale (≥34 out of 80). Univariate paired difference tests, multivariate random forest models, and cluster analyses were used to explore physiological response patterns across different social and non-social contexts. Our results suggest that social context is more reliably distinguishable than social phase, group size, or level of social threat, and that there is considerable variability in physiological response patterns even among distinguishable contexts. Implications for real-world context detection and future deployment of JITAIs are discussed.IEEE transactions on affective computingWearable Sensor-based Multimodal Physiological Responses of Socially Anxious Individuals in Social Contexts on Zoom.PMC12416631R01 MH132138Toner ERLone HTeachman BALarrazabal MABarnes LERucker MBoukhechba MCai LWang ZDatta DfalseWearable Sensor-based Multimodal Physiological Responses of Socially Anxious Individuals in Social Contexts on Zoom.Correctly identifying an individual's social context from passively worn sensors holds promise for delivering just-in-time adaptive interventions (JITAIs) to treat social anxiety. In this study, we present results using passively collected data from a within-subjects experiment that assessed physiological responses across different social contexts (i.e., alone vs. with others), social phases (i.e., pre- and post-interaction vs. during an interaction), social interaction sizes (i.e., dyadic vs. group interactions), and levels of social threat (i.e., implicit vs. explicit social evaluation). Participants in the study (<i>N</i> = 46) reported moderate to severe social anxiety symptoms as assessed by the Social Interaction Anxiety Scale (≥34 out of 80). Univariate paired difference tests, multivariate random forest models, and cluster analyses were used to explore physiological response patterns across different social and non-social contexts. Our results suggest that social context is more reliably distinguishable than social phase, group size, or level of social threat, and that there is considerable variability in physiological response patterns even among distinguishable contexts. Implications for real-world context detection and future deployment of JITAIs are discussed.2025-01-01T00:00:00Z2025 Jul-Sep2026-06-01T16:10:02.61Z2026-04-08T13:58:07.552ZS-EPMC124166314092723210.1109/taffc.2025.3562787